Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing

Nature Reviews Drug Discovery, 2023

Francesco Marchetti, Renato Cardoso, Connie L. Chen, ...

The GTTC is pleased to share its newest publication, “Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing,” published in Nature Reviews Drug Discovery. The commentary highlights the potential applications, advantages and challenges associated with ...

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Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review

Environmental and Molecular Mutagenesis, 2022

Douglas GR, Beevers C, Gollapudi B, Keig-Shevlin Z, Kirkland D, ...

This review was undertaken to assess whether the available data support the contention that there would be no substantial loss of mutations in rapidly proliferating tissues by increasing the sampling time from 3 to 28 days after the end of 28 days of dosing.

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