Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

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Validating and Using Cardiac NAMs for Toxicity Screening and Drug Development

International Journal of Toxicology, 2025

Pierson et al.

This work addresses longstanding challenges in drug development, where traditional animal models often fail to predict human cardiac outcomes. Through a multi-year FDA-funded grant, the committee assessed the performance of new approach methodologies (NAMs), including human-induced pluripotent stem cell–derived ...

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