This study from the HESI eSTAR miRNA Working Group is aimed to find biomarkers that can predict kidney damage.
Urinary MicroRNA biomarkers of nephrotoxicity in Macaca fascicularis
Regulatory Toxicology and Pharmacology, 2024
Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.
Regulatory Toxicology and Pharmacology, 2024
This study from the HESI eSTAR miRNA Working Group is aimed to find biomarkers that can predict kidney damage.
Regulatory Toxicology and Pharmacology, 2024
DART experts advocate for revised, science-driven dose selection criteria to produce relevant data ethically and responsibly. They urge ECHA to balance regulatory requirements with scientific pragmatism to better protect human health and animal welfare.
Clinical Pharmacology & Therapeutics, 2024
We are thrilled to announce the publication of a groundbreaking white paper by the HESI Immuno-Safety Technical Committee, now available in Clinical Pharmacology & Therapeutics.
Journal of Pharmacological and Toxicological Methods, 2024
The Health and Environmental Sciences Institute (HESI) Cardiac Safety Technical Committee (CSTC) has made significant strides in improving cardiovascular (CV) safety in drug development.
Journal of Applied Toxicology, 2024
A newly published study from the Botanical Safety Consortium used computational models to predict the physiochemical and pharmacokinetic properties of botanical constituents.
Journal of Pharmacological and Toxicological Methods, 2024
The Health and Environmental Sciences Institute (HESI) Cardiac Safety Committee designed and created a publicly accessible database with an initial set of 128 pharmacologically defined pharmaceutical agents, many with known cardiotoxic properties.
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