HESI Annual Meetings

HESI Annual Meeting

June 11-12, 2019

HESI AT THIRTY:
THE PAST, PRESENT AND FUTURE OF COLLABORATIVE SCIENCE

The Westin - Alexandria, VA

Tuesday 11 June 2019


9:00 AM	Welcome & Meeting Goals
9:15 AM	Why HESI Matters: A Perspective on 30 Years of Collaborative Science and Its Role Today
	Dr. Lois Lehman-McKeeman, Bristol-Myers Squibb, HESI Chair of Board
9:45 AM	HESI CITE Lectures – Moderator: Charlene McQueen, University of Arizona, HESI President. The HESI Combining Interdisciplinary and Translational Expertise (CITE) initiative is an ongoing outreach series that promotes discussion and progress on opportunities for, and challenges in, the application of interdisciplinary, multidisciplinary, and translational sciences to improve human and environmental health outcomes.
	The Exposome: Measuring Exposures on a Global Scale
	Dr. Gary Miller, Vice Dean for Research Strategy and Innovation, Mailman School of Public Health, Columbia University
	Acceptable Failure, Innovation & Multidisciplinary Research
	Dr. Martin Philbert, Provost, University of Michigan
11:15 AM	Break
11:30 AM	What will collaborative, multidisciplinary science look like in 2030? How will it adapt and respond to changing scientific, economic, and societal opportunities and pressures?
	Moderator: Dr. Martin Philbert; Panelists: Dr. Gary Miller (Columbia University, USA), Dr. Maya Leventer-Roberts (Clalit Research Institute, Israel), Dr. Ned Wakeman (Alderly Park Accelerator, UK), and Dr. Flavio Zambrone (State University of Campinas, Brazil)
12:00 PM	Lunch
12:15 PM	HESI Scientific Committee Leadership Working Session
1:15 PM	The Future of HESI Science: Where is HESI's programming headed?
	Dr. Syril Pettit, HESI Executive Director, and Dr. Michelle Embry, HESI Associate Director
2:00 PM	Featured Program Developments at HESI – This session highlights selected HESI scientific programs that have achieved key milestones and/or are actively pursuing new research programs (25 minutes each including questions). Moderator: Dr. Jon Cook, Pfizer, HESI Vice President.
	Paving the Way to UVCB Risk Assessment
	Dr. Sandrine Deglin, HESI, on behalf of the UVCB Committee
	Improving Health Outcomes for High Risk Neonates via Safer Therapeutic Intervention
	Dr. Kary Thompson, Bristol-Myers Squibb, on behalf of the Developmental and Reproductive Toxicology (DART) Committee
	Innovating Genomic Research via Error-Corrected Sequencing Methodologies
	Bob Young, MilliporeSigma, BioReliance Testing Services, on behalf of the Genetic Toxicology Technical Committee
	Challenging the Status Quo: Mechanistic and Human-Relevant Screening for CV Liabilities
	Dr. Brian Berridge, NIEHS National Toxicology Program, on behalf of the Cardiac Safety Committee
4:00 PM	Break
4:30 PM	Proposal for New Emerging Issues Project: Building an Exposure Science Network
	Dr. Michelle Embry, HESI Associate Director
5:00 PM	RNAi, Cancer, and Non-Coding RNA: From Discovery into Application for Health
	Keynote Speaker – Dr. Gregory Hannon, Cancer Research UK, Cambridge Institute
	Introduced by Dr. Tim Gant, Public Health England, Chair of HESI Emerging Issues Committee
	30th Anniversary Dinner Reception – Hummingbird Restaurant, Alexandria, Virginia

Wednesday 12 June 2019


8:30 AM	Welcome
8:40 AM	Can cancer risk assessment keep pace with evolving science and modalities? This session will explore the evolving landscape of tools, frameworks, and weight of evidence necessary to assess safety for evolving scientific modalities and methodologies from a carcinogenicity perspective. Moderator: Dr. Martin van den Berg, University of Utrecht, HESI Vice-Chair of Board.
8:45 AM	HESI’s Foundational Efforts in Cancer Risk Assessment & Transitions to Today
	Dr. Samuel Cohen, University of Nebraska Medical Center
9:20 AM	Carcinogenomic Approaches to Cancer Risk Assessment: Ready for Prime Time?
	Dr. Jan Willem van der Laan, Medicines Evaluation Board
9:55 AM	Cancer Risk Assessment of Immunomodulatory Therapies
	Dr. Hervé Lebrec, Amgen
10:30 AM	Break
10:50 AM	A Problem Formulation-Based Approach to the Risk Assessment of Crop Protection Products Acting via RNA Interference
	Dr. Kevin Leiner, Syngenta
11:20 AM	Legal and Regulatory Considerations in Safety Assessment of New Technologies
	Dr. Gary Marchant, Arizona State University
12:00 PM	Lunch
1:15 PM	Perspectives on Modern Approaches for Risk Assessment Under Canada’s Chemicals Management Plan: Building Confidence in Collaboration
	Keynote Address – Dr. Tara Barton-Maclaren, Research Manager, Healthy Environments and Consumer Safety Branch, Health Canada
1:50 PM	Panel discussion on opportunities, limitations, and cautions for collaborations to support or drive progress in integrating computational approaches for risk/safety assessment
	Moderator: Dr. Lois Lehman-McKeeman; Panelists: Dr. Tara Barton-Maclaren (Health Canada), Dr. Brian Berridge (NIEHS NTP), Dr. Masayuki Fujita (Sumitomo Chemical), and TBD
2:30 PM	Closing Remarks & Awards
2:45 PM	Adjourn

Hotel Information

The Westin Alexandria
400 Courthouse Square
Alexandria, VA 22314

Room rate: $254 per night for single or double occupancy
Deadline to book room: Thursday, May 16, 2019
Click here to reserve your room within the room block.