Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools

Food and Chemical Toxicology, 2024

Waidyanatha et al.

Increases in botanical use, encompassing herbal medicines and dietary supplements, have underlined a critical need for an advancement in safety assessment methodologies. This manuscript highlights: 1) Botanical Safety Consortium's strategy for botanical selection, sourcing, and preparation of extracts to be used in in ...

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HESI workshop summary: Interpretation of developmental and reproductive toxicity endpoints and the impact on data interpretation of adverse events

Birth Defects Research, 2024

Green et al.

Output from the HESI DART workshop entitled, “Interpretation of Developmental and Reproductive Toxicology in Regulatory Contexts and Frameworks” has been published. The purpose of the workshop was to capture key consensus approaches used to assess DART risks associated with chemical and pharmaceutical product exposure ...

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A (not) new Rx: Quality Improvement for NAM

Regulatory Toxicology and Pharmacology, 2024

Syril D. Pettit

This Commentary asserts that the challenges of realizing the systems-level changes needed to catalyze the broad-scale adoption and use of New Approach Methodologies (NAMs) may be less unique than perceived to date, and points to specific opportunities to learn from decades of experience (both positive and negative) from the ...

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