Upcoming Events

2021 HESI Annual Meeting

Virtual meeting, hosted by HESI

Save the date for the 2021 HESI Annual Meeting! Check back soon for program and registration details.

Read more

HESI Sessions at SOT 2021

Virtual meeting & ToxExpo, hosted by the Society of Toxicology (SOT)

The HESI Translational Biomarkers of Neurotoxicity (NeuTox) Committee, Developmental and Reproductive Toxicology (DART) Committee, and Botanical Safety Consortium (BSC) will present their work at the 2021 Society of Toxicology (SOT) virtual Annual Meeting & ToxExpo on 22-24 March 2021. Additionally, Dr. Syril ...

Read more

Quantitative Interpretation of Genetic Toxicity Dose Response Data for Risk Assessment and Regulatory Decision-Making: Current Status, Persistent Challenges, and Emerging Priorities

Virtual workshop, hosted by HESI and the Environmental Mutagenesis and Genomics Society (EMGS)

The workshop will (1) provide a brief overview of the state of the science regarding quantitative interpretation of genetic toxicity dose-response data, including a brief overview of the BMD combined covariate approach for potency ranking and MOA investigation, (2) a summary of recent genotoxicity risk assessment case ...

Read more

PATB Committee Protein Toxins Workshop

Virtual workshop, hosted by the HESI PATB Committee

The HESI Protein Allergens, Toxins, and Bioinformatics (PATB) Committee is hosting a virtual workshop focusing on the state of the science for a wide array of protein toxins classes, MOAs, structures, activity, and general biology. Additionally, the workshop will cover the bioinformatics analysis of protein toxins and how ...

Read more

THRIVE Letters of Intent: Submission Now Open!

Online submission, via HESI THRIVE

HESI THRIVE is a seed grant program that is innovating translational research and improving quality of life after cancer. By providing researchers with both seed funding and access to critical networks, THRIVE enhances the visibility of the patient need, the value of the research, and the reasons that larger funding entities ...

Read more

WP_Query Object
(
    [query] => Array
        (
            [post_type] => event
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [before] => 
            [after] => 
            [tags] => 
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => OR
                    [0] => Array
                        (
                            [key] => _ilsi_date
                            [value] => Array
                                (
                                    [0] => 2020-01-01
                                    [1] => 2020-12-31
                                )

                            [compare] => BETWEEN
                        )

                    [1] => Array
                        (
                            [key] => _ilsi_date
                            [value] => 2020-12-31
                            [compare] => <
                        )

                    [2] => Array
                        (
                            [key] => _ilsi_end_date
                            [value] => 2021-03-02
                            [compare] => >=
                        )

                )

            [paged] => 1
            [meta_key] => _ilsi_date
            [orderby] => meta_value
            [order] => DESC
        )

    [query_vars] => Array
        (
            [post_type] => event
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [before] => 
            [after] => 
            [tags] => 
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => OR
                    [0] => Array
                        (
                            [key] => _ilsi_date
                            [value] => Array
                                (
                                    [0] => 2020-01-01
                                    [1] => 2020-12-31
                                )

                            [compare] => BETWEEN
                        )

                    [1] => Array
                        (
                            [key] => _ilsi_date
                            [value] => 2020-12-31
                            [compare] => <
                        )

                    [2] => Array
                        (
                            [key] => _ilsi_end_date
                            [value] => 2021-03-02
                            [compare] => >=
                        )

                )

            [paged] => 1
            [meta_key] => _ilsi_date
            [orderby] => meta_value
            [order] => DESC
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => 
            [menu_order] => 
            [embed] => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [suppress_filters] => 
            [ignore_sticky_posts] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                    [0] => Array
                        (
                            [key] => _ilsi_date
                        )

                    [1] => Array
                        (
                            [0] => Array
                                (
                                    [key] => _ilsi_date
                                    [value] => Array
                                        (
                                            [0] => 2020-01-01
                                            [1] => 2020-12-31
                                        )

                                    [compare] => BETWEEN
                                )

                            [1] => Array
                                (
                                    [key] => _ilsi_date
                                    [value] => 2020-12-31
                                    [compare] => <
                                )

                            [2] => Array
                                (
                                    [key] => _ilsi_end_date
                                    [value] => 2021-03-02
                                    [compare] => >=
                                )

                            [relation] => OR
                        )

                    [relation] => AND
                )

            [relation] => AND
            [meta_table] => wp_postmeta
            [meta_id_column] => post_id
            [primary_table] => wp_posts
            [primary_id_column] => ID
            [table_aliases:protected] => Array
                (
                    [0] => wp_postmeta
                    [1] => mt1
                )

            [clauses:protected] => Array
                (
                    [wp_postmeta] => Array
                        (
                            [key] => _ilsi_date
                            [compare] => =
                            [compare_key] => =
                            [alias] => wp_postmeta
                            [cast] => CHAR
                        )

                    [mt1] => Array
                        (
                            [key] => _ilsi_date
                            [value] => Array
                                (
                                    [0] => 2020-01-01
                                    [1] => 2020-12-31
                                )

                            [compare] => BETWEEN
                            [compare_key] => =
                            [alias] => mt1
                            [cast] => CHAR
                        )

                    [mt1-1] => Array
                        (
                            [key] => _ilsi_date
                            [value] => 2020-12-31
                            [compare] => <
                            [compare_key] => =
                            [alias] => mt1
                            [cast] => CHAR
                        )

                    [mt1-2] => Array
                        (
                            [key] => _ilsi_end_date
                            [value] => 2021-03-02
                            [compare] => >=
                            [compare_key] => =
                            [alias] => mt1
                            [cast] => CHAR
                        )

                )

            [has_or_relation:protected] => 1
        )

    [date_query] => 
    [request] => SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID FROM wp_posts  INNER JOIN wp_postmeta ON ( wp_posts.ID = wp_postmeta.post_id )  INNER JOIN wp_postmeta AS mt1 ON ( wp_posts.ID = mt1.post_id ) WHERE 1=1  AND ( 
  wp_postmeta.meta_key = '_ilsi_date' 
  AND 
  ( 
    ( mt1.meta_key = '_ilsi_date' AND mt1.meta_value BETWEEN '2020-01-01' AND '2020-12-31' ) 
    OR 
    ( mt1.meta_key = '_ilsi_date' AND mt1.meta_value < '2020-12-31' ) 
    OR 
    ( mt1.meta_key = '_ilsi_end_date' AND mt1.meta_value >= '2021-03-02' )
  )
) AND wp_posts.post_type = 'event' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled') GROUP BY wp_posts.ID ORDER BY wp_postmeta.meta_value DESC LIMIT 0, 6
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 23777
                    [post_author] => 14
                    [post_date] => 2021-01-05 18:25:28
                    [post_date_gmt] => 2021-01-05 18:25:28
                    [post_content] => 
                    [post_title] => 2021 HESI Annual Meeting
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => 2021-hesi-annual-meeting
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2021-01-05 18:26:21
                    [post_modified_gmt] => 2021-01-05 18:26:21
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=event&p=23777
                    [menu_order] => 0
                    [post_type] => event
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [1] => WP_Post Object
                (
                    [ID] => 23871
                    [post_author] => 14
                    [post_date] => 2021-02-22 16:02:13
                    [post_date_gmt] => 2021-02-22 16:02:13
                    [post_content] => 
                    [post_title] => The Contributions of Environmental Epidemiologic Research to Causal Attribution and Risk Assessment
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => environmental-epidemiology-committee-webinar-series
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2021-02-23 17:02:43
                    [post_modified_gmt] => 2021-02-23 17:02:43
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=event&p=23871
                    [menu_order] => 0
                    [post_type] => event
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [2] => WP_Post Object
                (
                    [ID] => 23872
                    [post_author] => 14
                    [post_date] => 2021-02-22 16:15:34
                    [post_date_gmt] => 2021-02-22 16:15:34
                    [post_content] => 
                    [post_title] => HESI Sessions at SOT 2021
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => hesi-sessions-at-sot-2021
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2021-02-23 16:04:26
                    [post_modified_gmt] => 2021-02-23 16:04:26
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=event&p=23872
                    [menu_order] => 0
                    [post_type] => event
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [3] => WP_Post Object
                (
                    [ID] => 23708
                    [post_author] => 14
                    [post_date] => 2020-10-27 17:55:16
                    [post_date_gmt] => 2020-10-27 17:55:16
                    [post_content] => 
                    [post_title] => Quantitative Interpretation of Genetic Toxicity Dose Response Data for Risk Assessment and Regulatory Decision-Making: Current Status, Persistent Challenges, and Emerging Priorities
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => quantitative-interpretation-of-genetic-toxicity-dose-response-data-for-risk-assessment-and-regulatory-decision-making-current-status-persistent-challenges-and-emerging-priorities
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2020-10-30 15:26:58
                    [post_modified_gmt] => 2020-10-30 15:26:58
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=event&p=23708
                    [menu_order] => 0
                    [post_type] => event
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [4] => WP_Post Object
                (
                    [ID] => 22887
                    [post_author] => 14
                    [post_date] => 2020-08-04 09:30:56
                    [post_date_gmt] => 2020-08-04 14:30:56
                    [post_content] => 
	

 

The HESI Protein Allergens, Toxins, and Bioinformatics (PATB) Committee is hosting a virtual workshop focusing on the state of the science for a wide array of protein toxins classes, MOAs, structures, activity, and general biology. Additionally, the workshop will cover the bioinformatics analysis of protein toxins and how to leverage computational biology for protein toxins identification/characterization, with in silico approaches.

The Protein Toxins Workshop will serve the dual purpose of learning from the experts in the field about the state of the science as well as assessing the translation of knowledge to practical applications, e.g., into weight-of-evidence approaches for the safety assessment of biotechnology products. The workshop aims to gain insight into how feasible/useful (or not) a protein toxin database could be in risk assessment/product development. This meeting will serve as an informational platform about HESI and will demonstrate the advances in protein toxins research, presented by international experts, and will help inform the development of novel approaches for the identification and classification of potential toxicity risk in novel proteins.

Details

  • Date: Wednesday, 21 October 2020 - Thursday, 22 October 2020
  • Time: 9:00 AM - 12:00 PM EST
  • Registration: Details coming soon
PATC_resize

Workshop Program Outline (subject to change)

Wednesday, 21 October 2020

  • 9:00 AM - Opening Remarks (Dr. Laura Privalle, BASF Corporation)
    • From protein toxins to biotechnology products
    • Setting the stage; considerations for publication of meeting report
  • 9:30 AM - Brief Codex Discussion
    • Allergenicity assessment vs. toxins/toxicity assessment
  • 10:00 AM - Terrestrial Toxins
  • 11:30 AM - Marine Toxins

 

Thursday, 22 October 2020

  • 9:00 AM - Bacterial Toxins
  • 10:30 AM - Bioinformatics & Computational Biology in Protein Toxins Research

 

For more information, please contact the PATB Committee's Senior Scientific Program Manager, Dr. Lucilia Mouriès at lmouries@hesiglobal.org.

[post_title] => PATB Committee Protein Toxins Workshop [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => patb-committee-protein-toxins-workshop [to_ping] => [pinged] => [post_modified] => 2021-02-04 22:52:34 [post_modified_gmt] => 2021-02-04 22:52:34 [post_content_filtered] => [post_parent] => 0 [guid] => https://hesiglobal.org/?post_type=event&p=22887 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [5] => WP_Post Object ( [ID] => 23732 [post_author] => 14 [post_date] => 2020-10-29 14:53:54 [post_date_gmt] => 2020-10-29 14:53:54 [post_content] => [post_title] => THRIVE Letters of Intent: Submission Now Open! [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => thrive-letters-of-intent-submission-now-open [to_ping] => [pinged] => [post_modified] => 2020-11-02 18:33:47 [post_modified_gmt] => 2020-11-02 18:33:47 [post_content_filtered] => [post_parent] => 0 [guid] => https://hesiglobal.org/?post_type=event&p=23732 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) ) [post_count] => 6 [current_post] => -1 [in_the_loop] => [post] => WP_Post Object ( [ID] => 23777 [post_author] => 14 [post_date] => 2021-01-05 18:25:28 [post_date_gmt] => 2021-01-05 18:25:28 [post_content] => [post_title] => 2021 HESI Annual Meeting [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => 2021-hesi-annual-meeting [to_ping] => [pinged] => [post_modified] => 2021-01-05 18:26:21 [post_modified_gmt] => 2021-01-05 18:26:21 [post_content_filtered] => [post_parent] => 0 [guid] => https://hesiglobal.org/?post_type=event&p=23777 [menu_order] => 0 [post_type] => event [post_mime_type] => [comment_count] => 0 [filter] => raw ) [comment_count] => 0 [current_comment] => -1 [found_posts] => 163 [max_num_pages] => 28 [max_num_comment_pages] => 0 [is_single] => [is_preview] => [is_page] => [is_archive] => [is_date] => [is_year] => [is_month] => [is_day] => [is_time] => [is_author] => [is_category] => [is_tag] => [is_tax] => [is_search] => [is_feed] => [is_comment_feed] => [is_trackback] => [is_home] => 1 [is_privacy_policy] => [is_404] => [is_embed] => [is_paged] => [is_admin] => [is_attachment] => [is_singular] => [is_robots] => [is_favicon] => [is_posts_page] => [is_post_type_archive] => [query_vars_hash:WP_Query:private] => 6d61cdc88dbedc57e193cb0cdea8cf82 [query_vars_changed:WP_Query:private] => 1 [thumbnails_cached] => [stopwords:WP_Query:private] => [compat_fields:WP_Query:private] => Array ( [0] => query_vars_hash [1] => query_vars_changed ) [compat_methods:WP_Query:private] => Array ( [0] => init_query_flags [1] => parse_tax_query ) )

Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-3859

740 15th Street NW, Suite 600
Washington, DC 20005

Stay Informed

Sign up for our monthly e-newsletter.