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HESI DART Workshop: Strategies for Oligonucleotides

October 17, 2023 – October 18, 2023

Hybrid, HESI Offices, Washington DC

This workshop will consider application of DART principles to fit attributes of ASOs, siRNAs and other oligonucleotide therapeutics and highlight gaps and challenges associated with determining the most appropriate strategies to account for potential risk to a varied patient population and spectrum of disease conditions.

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HESI 2023 Annual Meeting

June 7, 2023 – June 8, 2023

Central London, United Kingdom

HESI 2023 Annual Meeting: New Approach Methodologies for Safety Assessment – from Aspiration to Implementation. A joint HESI and UK National Center for the 3Rs Event.

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Quantitative Interpretation of Genetic Toxicity Dose Response Data for Risk Assessment and Regulatory Decision-Making: Current Status, Persistent Challenges, and Emerging Priorities

December 3, 2020

Virtual workshop, hosted by HESI and the Environmental Mutagenesis and Genomics Society (EMGS)

The workshop will (1) provide a brief overview of the state of the science regarding quantitative interpretation of genetic toxicity dose-response data, including a brief overview of the BMD combined covariate approach for potency ranking and MOA investigation, (2) a summary of recent genotoxicity risk assessment case ...

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Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-3859

740 15th Street NW, Suite 600
Washington, DC 20005

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