Microarrays provide an unprecedented opportunity for comprehensive concurrent analysis of thousands of genes.
The Utility of DNA Microarrays for Characterizing Genotoxicity
Environmental Health Perspectives, 2004
Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.
Environmental Health Perspectives, 2004
Microarrays provide an unprecedented opportunity for comprehensive concurrent analysis of thousands of genes.
Environmental Health Perspectives, 2004
The value of genomic approaches in hypothesis generation is being realized as a tool for understanding toxicity and consequently contributing to an assessment of drug and chemical safety.
Environmental Health Perspectives, 2004
In 1999 the membership of the International Life Sciences Institute (ILSI) Health and Environmental Sciences Institute (HESI) formed a multisector consortium to address challenges associated with the integration of genomics data into risk assessment (Pennie et al. 2004).
Environmental Health Perspectives, 2004
A significant limitation to the analytical accuracy and precision of dual-labeled spotted cDNA microarrays is the signal error due to dye bias.
Environmental Health Perspectives, 2004
Within the International Life Sciences Institute Committee on Genomics, a working group was formed to focus on the application of microarray technology to preclinical assessments of drug-induced nephrotoxicity.
Environmental Health Perspectives, 2004
DNA microarrays and related tools offer promise for identification of pathways involved in toxic responses to xenobiotics.
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