Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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The Pig as a Model of Developmental Immunology

Human and Experimental Toxicology, 2002

Rothkötter HJ, Sowa E, Pabst R
  • HESI - Health and Environmental Sciences Institute

There are many limitations to analyse the developing immune system in humans, thus there is need for experimental animal models to study the environmental influences during the ontogeny of the immune system.

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The Predictivity of the Toxicity of Pharmaceuticals in Humans From Animal Data—An Interim Assessment

Toxicology Letters, 1998

Olson H, Betton G, Stritar J, Robinson D
  • HESI - Health and Environmental Sciences Institute

This project was undertaken by the International Life Sciences Institute's Health and Environmental Sciences Institute (ILSI-HESI) to develop an improved understanding of the extent to which various types of human toxicities (HTs) manifested during clinical trials could be predicted from standard toxicology studies.

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The Rat microRNA Body Atlas: Evaluation of the microRNA Content of Rat Organs Through Deep Sequencing and Characterization of Pancreas Enriched miRNAs as Biomarkers of Pancreatic Toxicity in the Rat and Dog

BMC Genomics, 2016

Smith A, Calley J, Mathur S, Qian HR, Wu H, Farmen M, Caiment F, ...

MicroRNAs (miRNA) are ~19-25 nucleotide long RNA molecules that fine tune gene expression through the inhibition of translation or degradation of the mRNA through incorporation into the RNA induced silencing complex (RISC). MicroRNAs are stable in the serum and plasma, are detectable in a wide variety of ...

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