Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Breslin WJ, Paulman A, Sun‐Lin D, Goldstein KM, Derr A
- HESI - Health and Environmental Sciences Institute
The objective of this study was to evaluate the utility of plasma Inhibin B (InhB) as a biomarker of testicular injury in adult rats following short-term exposure to the known Sertoli cell toxicants mono-2-ethylhexyl phthalate (MEHP), 1,3 dinitrobenzene (DNB), or carbendazim (CBZ).
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Coulson M, Mitchard T, Bickerton S, Harris J, Betts C, Stewart J
- HESI - Health and Environmental Sciences Institute
This study examined the correlation between Inhibin B and testicular pathology.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Chapin RE, Alvey JD, Goldstein RA, Dokmanovich MG, Reagan WJ, ...
- HESI - Health and Environmental Sciences Institute
Serum Inhibin B was measured in two studies of known testis-toxic drug candidates.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Ziejewski MK, Vidal JD, Stanislaus D, Apostoli A, Chowdhury P, ...
- HESI - Health and Environmental Sciences Institute
In a repeat oral dose toxicity study, all of 16 male rats given 100 mg/kg/day GSK1322888 sustained testicular injury after 4 weeks of treatment; the findings were not reversible after 12 weeks off-dose.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Enright BP, Tornesi B, Lorenz H, Whitney K
- HESI - Health and Environmental Sciences Institute
This study was conducted as part of an ILSI-HESI consortium effort to assess the utility of circulating inhibin B as an early biomarker of testicular toxicity in rats.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Sonee M, Bogdan N, Hall L, Bryant S, Vinken P
- HESI - Health and Environmental Sciences Institute
This study was conducted as part of an ILSI-HESI International Life Sciences Institute-Health & Environmental Sciences Institute consortium effort to assess the utility of circulating Inhibin B as an early biomarker of Sertoli cell-specific testicular toxicity in rats.
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