A pilot toxicology database system has been created which is accessible on-line via the world-wide web or in-house via an intranet.
Towards the Creation of An International Toxicology Information Centre
Toxicology, 2005
Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.
Toxicology, 2005
A pilot toxicology database system has been created which is accessible on-line via the world-wide web or in-house via an intranet.
Environmental Health Perspectives, 2004
This study, designed and conducted as part of the International Life Sciences Institute working group on the Application of Genomics and Proteomics, examined the changes in the expression profile of genes associated with the administration of three different nephrotoxicants--cisplatin, gentamicin, and puromycin--to ...
Environmental Health Perspectives, 2004
Microarrays have the potential to significantly impact our ability to identify toxic hazards by the identification of mechanistically relevant markers of toxicity.
Environmental Health Perspectives, 2004
Consistency and coherence of gene expression data across multiple sites depends on several factors such as platform (oligo, cDNA, etc.), environmental conditions at each laboratory, and data quality.
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2004
Genotoxic stress triggers a variety of biological responses including the transcriptional activation of genes regulating DNA repair, cell survival and cell death.
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2004
During the safety evaluation process of new drugs and chemicals, a battery of genotoxicity tests is conducted starting with in vitro genotoxicity assays.
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