Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Li S, Davis B
- HESI - Health and Environmental Sciences Institute
Interpreting histopathology of the female rodent reproductive tract can be challenging in toxicity studies.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Rehm S, Solleveld HA, Portelli ST, Wier PJ
- HESI - Health and Environmental Sciences Institute
Idoxifene is a selective estrogen receptor modulator similar to tamoxifen but is no longer in pharmaceutical development due to adverse genitourinary effects in the clinic.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Rehm S, Stanislaus DJ, Wier PJ
- HESI - Health and Environmental Sciences Institute
Observations associated with drug-induced hyper- or hypoprolactinemia in rat toxicology studies may be similar and include increased ovarian weight due to increased presence of corpora lutea.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Rehm S, Stanislaus DJ, Williams AM
- HESI - Health and Environmental Sciences Institute
This report describes normal histology of tissues from immature female dogs and sequential microscopic changes that occur during different stages of the estrous cycle in ovary, uterus, vagina and mammary glands.
Journal of Immunotoxicology, 2007
Bugelski PJ, Kim C
- HESI - Health and Environmental Sciences Institute
The primary T-cell-dependent antibody response (TDAR) to antigens is widely used as a functional test in immunotoxicology.
Method, 2007
Dietert RR, Holsapple MP
- HESI - Health and Environmental Sciences Institute
Developmental immunotoxicity has gained increasing recognition as a significant factor influencing the risk of later life disease.
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