Toxicology and Applied Pharmacology, 2005
Sander M, Cadet J, Casciano DA, Galloway SM, Marnett LJ, Novak RF, ...
- HESI - Health and Environmental Sciences Institute
In April 2004, the Health and Environmental Sciences Institute, a branch of the International Life Sciences Institute, with support from the National Institute of Environmental Health Sciences, organized a workshop to discuss the biological significance of DNA adducts.
Clinical and Translational Allergy, 2018
Akkerdaas J, Totis M, Barnett B, Bell E, Davis T, Edrington T, ...
Susceptibility to pepsin digestion of candidate transgene products is regarded an important parameter in the weight-of-evidence approach for allergenicity risk assessment of genetically modified crops. It has been argued that protocols used for this assessment should better reflect physiological ...
Chemical Research in Toxicology, 2011
Escher BI, Cowan-Ellsberry CE, Dyer S, Embry MR, Erhardt S, ...
- HESI - Health and Environmental Sciences Institute
Binding of hydrophobic chemicals to colloids such as proteins or lipids is difficult to measure using classical microdialysis methods due to low aqueous concentrations, adsorption to dialysis membranes and test vessels, and slow kinetics of equilibration.
Integrated Environmental Assessment and Management, 2018
Greggs W, Burns T, Egeghy P, Embry MR, Fantke P, Gaborek B, ...
- HESI - Health and Environmental Sciences Institute
Most alternatives assessments (AAs) published to date are largely hazard‐based rankings, thereby ignoring potential differences in human and/or ecosystem exposures; as such, they may not represent a fully informed consideration of the advantages and disadvantages of possible alternatives. Building on the 2014 US ...
Environmental and Molecular Mutagenesis, 2013
Gollapudi BB, Johnson GE, Hernandez LG, Pottenger LH, ...
- HESI - Health and Environmental Sciences Institute
Genetic toxicology studies are required for the safety assessment of chemicals.
Environmental and Molecular Mutagenesis, 2022
Marc A. Beal, Marc Audebert, Tara Barton-Maclaren, ...
The Genetic Toxicology Technical Committee, under the Health and Environmental Sciences Institute, conducted a case study on 31 reference chemicals to evaluate the performance of IVIVE application to genotoxicity data.
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