Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications

Review of Laboratory-Based Terrestrial Bioaccumulation Assessment Approaches for Organic Chemicals: Current Status and Future Possibilities

In the last decade, interest has been renewed in approaches for the assessment of the bioaccumulation potential of chemicals, principally driven by the need to evaluate large numbers of chemicals as part of new chemical legislation, while reducing vertebrate test organism use called for in animal welfare ...

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Evaluation of Early Fetal Exposure to Vaginally-Administered Metronidazole in Pregnant Cynomolgus Monkeys

Given concern about potential embryo-fetal harm following seminal exposure to drugs with teratogenic potential, pharmaceutical companies use theoretical calculations to estimate seminal concentrations, maternal exposure, and distribution across the placenta to the embryo-fetal compartment for risk ...

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Use of the RISK21 Roadmap and Matrix: Human Health Risk Assessment of the Use of a Pyrethroid in Bed Netting

The HESI-coordinated RISK21 roadmap and matrix are tools that provide a transparent method to compare exposure and toxicity information and assess whether additional refinement is required to obtain the necessary precision level for a decision regarding safety.

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Contact Us

Health and Environmental Sciences Institute (HESI)

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