Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Investigation of Maternal and Fetal Exposure to an IgG2 Monoclonal Antibody Following Biweekly Intravaginal Administration to Cynomolgus Monkeys Throughout Pregnancy

Reproductive Toxicology, 2014

Moffat GJ, Davies R, Kwon G, Retter MW, Chellman GJ, Kanapuram S, ...
  • HESI - Health and Environmental Sciences Institute

To assess the potential for male-mediated drug transfer to their female partner and/or developing conceptus, vaginal uptake of a monoclonal antibody(mAb) biotherapeutic was assessed in cynomolgus monkeys.

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Investigative Immunotoxicology

2005

Woolhiser MR, Henry KS, Holsapple MP
  • HESI - Health and Environmental Sciences Institute

This book chapter was published in Ecoimmunotoxicology:  State of the Science.

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Juvenile Immunotoxicology

Toxicologic Pathology, 2012

Holsapple MP, O'Lone R
  • HESI - Health and Environmental Sciences Institute

Developmental immunotoxicity (DIT) testing is centered around the concern that exposure to immunotoxicants early in development may result in enhanced susceptibility of, or unique or more persistent effects on, the immune system, in comparison to adult exposure.

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Laboratory Variability Does Not Preclude Identification of Biological Functions Impacted by Hydroxyurea

Environmental and Molecular Mutagenesis, 2005

Müller A, Boitier E, Hu T, Carr GJ, Le Fèvre AC, Marchandeau JP, ...
  • HESI - Health and Environmental Sciences Institute

The multi-lab International Life Sciences Institute (ILSI) project on the application of genomics to risk assessment offered the unique opportunity to investigate the influence of variability within and between laboratories on identifying biologically relevant gene expression changes.

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