Given concern about potential embryo-fetal harm following seminal exposure to drugs with teratogenic potential, pharmaceutical companies use theoretical calculations to estimate seminal concentrations, maternal exposure, and distribution across the placenta to the embryo-fetal compartment for risk ...
Evaluation of Early Fetal Exposure to Vaginally-Administered Metronidazole in Pregnant Cynomolgus Monkeys
Reproductive Toxicology, 2015