Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Use of Terrestrial Field Studies in the Derivation of Bioaccumulation Potential of Chemicals

Integrated Environmental Assessment and Management, 2015

van den Brink NW, Arblaster JA, Bowman SR, Conder JM, Elliott JE, ...
  • HESI - Health and Environmental Sciences Institute

Field-based studies are an essential component of research addressing the behavior of organic chemicals, and a unique line of evidence that can be used to assess bioaccumulation potential in chemical registration programs and aid in development of associated laboratory and modeling efforts.

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Translational Biomarkers of Neurotoxicity: A Health and Environmental Sciences Institute Perspective on the Way Forward

Toxicological Sciences, 2015

Roberts RA, Aschner M, Calligaro D, Guilarte TR, Hanig JP, ...

Neurotoxicity has been linked to a number of common drugs and chemicals, yet efficient and accurate methods to detect it are lacking. There is a need for more sensitive and specific biomarkers of neurotoxicity that can help diagnose and predict neurotoxicity that are relevant across animal models and translational from ...

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Assessment of Cervical Passage of Vital Dyes in Pregnant, Nonpregnant, and Mated Rat and Mice

Reproductive Toxicology, 2015

Thompson KE, Rayhon SL, Bailey G, Delille P, McNerney ME
  • HESI - Health and Environmental Sciences Institute

Risk assessment for indirect exposure to small molecule pharmaceuticals in semen to the conceptus has traditionally been handled by calculations based on assumptions that any embryo-fetal exposure would be secondary to maternal absorption and redistribution.

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Evaluation of Early Fetal Exposure to Vaginally-Administered Metronidazole in Pregnant Cynomolgus Monkeys

Reproductive Toxicology, 2015

Thompson KE, Newcomb DL, Moffat GJ, Zalikowski J, Chellman GJ, ...
  • HESI - Health and Environmental Sciences Institute

Given concern about potential embryo-fetal harm following seminal exposure to drugs with teratogenic potential, pharmaceutical companies use theoretical calculations to estimate seminal concentrations, maternal exposure, and distribution across the placenta to the embryo-fetal compartment for risk ...

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Health and Environmental Sciences Institute (HESI)

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