Past Events

2019

Validation of New Approaches in Genetic Toxicology

Newark, Delaware, USA

Novel in vitro and in vivo assays have been developed to improve the reliability of tools employed for identification of genotoxic hazard. Several of the new assays can provide insight into mode-of-action (MoA). As emerging technologies generally used for evaluating human hazard and/or risk, these novel assays require rigorous evaluation and validation before use in a regulatory setting. Validating novel toxicology assaysis a continuing labor-intensive challenge. More specifically, many questions arise around choosing reference compounds, and comparing results against the current standard battery used for genotoxicity testing.

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Cancer Immunotherapies: Biology, Therapeutic Approaches, and Immune Related Safety Assessments

South San Francisco, California, USA

The field of immunotoxicology is a dynamic one in which changing public health concerns, novel biomedical research advances, and innovative technological developments constantly change the landscape and the way in which work is carried out and utilized. As this field requires combined expertise in both immunology and toxicology, the need for continued training and interdisciplinary interactions are critical for those who work within this field. This is essential both for those with an immunology background who seek to apply this expertise to drug development and safety, as well as those who wish to enhance their current drug safety expertise with a deeper understanding of immunology.

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FDA Cardiac Safety Workshop

Silver Spring, USA

FDA Public Workshop on Leveraging Human-Relevant Cardiomyocytes in Nonclinical Studies to Provide Mechanistic Insights into Cardiovascular Safety Liabilities

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