2018 HESI Annual Meeting
June 12, 2018 – June 13, 2018
Washington, DC, USA
June 12, 2018 – June 13, 2018
Washington, DC, USA
May 15, 2018 – May 16, 2018
Boston, Massachusetts, USA
The Cardiac Safety Committee convened a 2-day workshop to discuss mechanistic approaches to cardiovascular safety assessment.
May 2, 2018 – May 5, 2018
Montreal, Canada
For the second consecutive year, the CT-TRACS Committee will participate in a 4-day annual meeting organized by the International Society for Cellular Therapy.
April 18, 2018
Belgrade, Serbia
Continuing education course at IUTOX / CTDC.
April 4, 2018 – April 5, 2018
Munich , Germany
The field of immunotoxicology is a dynamic one in which changing public health concerns, novel biomedical research advances, and innovative technological developments constantly change the landscape and the way in which work is carried out and utilized. As this field requires combined expertise in both immunology and ...
March 22, 2018 – March 23, 2018
Potsdam, Germany
Applied genetic toxicology is undergoing a major paradigm shift towards changing the strategies employed for assessment of chemically-induced genomic damage, evaluation methods of the mechanisms by which that damage translates into adverse effects, and the quantitative methods used to interpret dose-response data. This ...
WP_Query Object
(
[query] => Array
(
[post_type] => event
[posts_per_page] => 6
[type] =>
[area] =>
[before] => 2025-05-15
[after] =>
[tags] =>
[showtitle] => false
[meta_query] => Array
(
[relation] => Array
(
[0] => AND
[1] => AND
)
[0] => Array
(
[key] => _ilsi_date
[value] => 2025-05-15
[compare] => <=
)
[1] => Array
(
[key] => _ilsi_end_date
[value] => 2025-05-15
[compare] => <=
)
[2] => Array
(
[key] => _ilsi_date
[value] => Array
(
[0] => 2018-01-01
[1] => 2018-12-31
)
[compare] => BETWEEN
)
[3] => Array
(
[key] => _ilsi_date
[value] => 2018-12-31
[compare] => <
)
)
[paged] => 2
[meta_key] => _ilsi_date
[orderby] => meta_value
[order] => DESC
)
[query_vars] => Array
(
[post_type] => event
[posts_per_page] => 6
[type] =>
[area] =>
[before] => 2025-05-15
[after] =>
[tags] =>
[showtitle] => false
[meta_query] => Array
(
[relation] => Array
(
[0] => AND
[1] => AND
)
[0] => Array
(
[key] => _ilsi_date
[value] => 2025-05-15
[compare] => <=
)
[1] => Array
(
[key] => _ilsi_end_date
[value] => 2025-05-15
[compare] => <=
)
[2] => Array
(
[key] => _ilsi_date
[value] => Array
(
[0] => 2018-01-01
[1] => 2018-12-31
)
[compare] => BETWEEN
)
[3] => Array
(
[key] => _ilsi_date
[value] => 2018-12-31
[compare] => <
)
)
[paged] => 2
[meta_key] => _ilsi_date
[orderby] => meta_value
[order] => DESC
[error] =>
[m] =>
[p] => 0
[post_parent] =>
[subpost] =>
[subpost_id] =>
[attachment] =>
[attachment_id] => 0
[name] =>
[pagename] =>
[page_id] => 0
[second] =>
[minute] =>
[hour] =>
[day] => 0
[monthnum] => 0
[year] => 0
[w] => 0
[category_name] =>
[tag] =>
[cat] =>
[tag_id] =>
[author] =>
[author_name] =>
[feed] =>
[tb] =>
[meta_value] =>
[preview] =>
[s] =>
[sentence] =>
[title] =>
[fields] =>
[menu_order] =>
[embed] =>
[category__in] => Array
(
)
[category__not_in] => Array
(
)
[category__and] => Array
(
)
[post__in] => Array
(
)
[post__not_in] => Array
(
)
[post_name__in] => Array
(
)
[tag__in] => Array
(
)
[tag__not_in] => Array
(
)
[tag__and] => Array
(
)
[tag_slug__in] => Array
(
)
[tag_slug__and] => Array
(
)
[post_parent__in] => Array
(
)
[post_parent__not_in] => Array
(
)
[author__in] => Array
(
)
[author__not_in] => Array
(
)
[search_columns] => Array
(
)
[ignore_sticky_posts] =>
[suppress_filters] =>
[cache_results] => 1
[update_post_term_cache] => 1
[update_menu_item_cache] =>
[lazy_load_term_meta] => 1
[update_post_meta_cache] => 1
[nopaging] =>
[comments_per_page] => 50
[no_found_rows] =>
)
[tax_query] => WP_Tax_Query Object
(
[queries] => Array
(
)
[relation] => AND
[table_aliases:protected] => Array
(
)
[queried_terms] => Array
(
)
[primary_table] => wp_posts
[primary_id_column] => ID
)
[meta_query] => WP_Meta_Query Object
(
[queries] => Array
(
[0] => Array
(
[key] => _ilsi_date
)
[1] => Array
(
[0] => Array
(
[key] => _ilsi_date
[value] => 2025-05-15
[compare] => <=
)
[1] => Array
(
[key] => _ilsi_end_date
[value] => 2025-05-15
[compare] => <=
)
[2] => Array
(
[key] => _ilsi_date
[value] => Array
(
[0] => 2018-01-01
[1] => 2018-12-31
)
[compare] => BETWEEN
)
[3] => Array
(
[key] => _ilsi_date
[value] => 2018-12-31
[compare] => <
)
[relation] => AND
)
[relation] => AND
)
[relation] => AND
[meta_table] => wp_postmeta
[meta_id_column] => post_id
[primary_table] => wp_posts
[primary_id_column] => ID
[table_aliases:protected] => Array
(
[0] => wp_postmeta
[1] => mt1
[2] => mt2
[3] => mt3
[4] => mt4
)
[clauses:protected] => Array
(
[wp_postmeta] => Array
(
[key] => _ilsi_date
[compare] => =
[compare_key] => =
[alias] => wp_postmeta
[cast] => CHAR
)
[mt1] => Array
(
[key] => _ilsi_date
[value] => 2025-05-15
[compare] => <=
[compare_key] => =
[alias] => mt1
[cast] => CHAR
)
[mt2] => Array
(
[key] => _ilsi_end_date
[value] => 2025-05-15
[compare] => <=
[compare_key] => =
[alias] => mt2
[cast] => CHAR
)
[mt3] => Array
(
[key] => _ilsi_date
[value] => Array
(
[0] => 2018-01-01
[1] => 2018-12-31
)
[compare] => BETWEEN
[compare_key] => =
[alias] => mt3
[cast] => CHAR
)
[mt4] => Array
(
[key] => _ilsi_date
[value] => 2018-12-31
[compare] => <
[compare_key] => =
[alias] => mt4
[cast] => CHAR
)
)
[has_or_relation:protected] =>
)
[date_query] =>
[request] =>
SELECT SQL_CALC_FOUND_ROWS wp_posts.ID
FROM wp_posts INNER JOIN wp_postmeta ON ( wp_posts.ID = wp_postmeta.post_id ) INNER JOIN wp_postmeta AS mt1 ON ( wp_posts.ID = mt1.post_id ) INNER JOIN wp_postmeta AS mt2 ON ( wp_posts.ID = mt2.post_id ) INNER JOIN wp_postmeta AS mt3 ON ( wp_posts.ID = mt3.post_id ) INNER JOIN wp_postmeta AS mt4 ON ( wp_posts.ID = mt4.post_id )
WHERE 1=1 AND (
wp_postmeta.meta_key = '_ilsi_date'
AND
(
( mt1.meta_key = '_ilsi_date' AND mt1.meta_value <= '2025-05-15' )
AND
( mt2.meta_key = '_ilsi_end_date' AND mt2.meta_value <= '2025-05-15' )
AND
( mt3.meta_key = '_ilsi_date' AND mt3.meta_value BETWEEN '2018-01-01' AND '2018-12-31' )
AND
( mt4.meta_key = '_ilsi_date' AND mt4.meta_value < '2018-12-31' )
)
) AND ((wp_posts.post_type = 'event' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
GROUP BY wp_posts.ID
ORDER BY wp_postmeta.meta_value DESC
LIMIT 6, 6
[posts] => Array
(
[0] => WP_Post Object
(
[ID] => 6586
[post_author] => 8
[post_date] => 2018-01-10 11:49:39
[post_date_gmt] => 2018-01-10 16:49:39
[post_content] =>
[post_title] => 2018 HESI Annual Meeting
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => 2018hesiannualmeeting
[to_ping] =>
[pinged] =>
[post_modified] => 2018-01-10 11:49:39
[post_modified_gmt] => 2018-01-10 16:49:39
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=6586
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[1] => WP_Post Object
(
[ID] => 6725
[post_author] => 8
[post_date] => 2018-02-08 16:13:54
[post_date_gmt] => 2018-02-08 21:13:54
[post_content] =>
[post_title] => Cardiac Safety Committee 2018 Workshop
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => cardiacsafetycommittee2018workshop
[to_ping] =>
[pinged] =>
[post_modified] => 2020-10-28 13:28:47
[post_modified_gmt] => 2020-10-28 13:28:47
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=6725
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[2] => WP_Post Object
(
[ID] => 6917
[post_author] => 15
[post_date] => 2018-04-13 09:07:34
[post_date_gmt] => 2018-04-13 14:07:34
[post_content] =>
[post_title] => ISCT 2018
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => isct-2018
[to_ping] =>
[pinged] =>
[post_modified] => 2018-04-13 09:07:34
[post_modified_gmt] => 2018-04-13 14:07:34
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=6917
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[3] => WP_Post Object
(
[ID] => 5539
[post_author] => 9
[post_date] => 2017-11-07 14:42:00
[post_date_gmt] => 2017-11-07 19:42:00
[post_content] =>
[post_title] => RISK21 Continuing Education Course at IUTOX / CTDC
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => continuing-education-course-at-iutox-ctdc
[to_ping] =>
[pinged] =>
[post_modified] => 2024-09-25 20:24:21
[post_modified_gmt] => 2024-09-25 20:24:21
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=5539
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[4] => WP_Post Object
(
[ID] => 6660
[post_author] => 11
[post_date] => 2018-01-17 11:04:07
[post_date_gmt] => 2018-01-17 16:04:07
[post_content] =>
[post_title] => T-Cell Biology and Application to Immunopharmacology and Immunotoxicology Course
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => immunotox-training-course-2018
[to_ping] =>
[pinged] =>
[post_modified] => 2020-10-28 15:01:28
[post_modified_gmt] => 2020-10-28 15:01:28
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=6660
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[5] => WP_Post Object
(
[ID] => 6968
[post_author] => 12
[post_date] => 2018-05-18 09:10:09
[post_date_gmt] => 2018-05-18 14:10:09
[post_content] =>
Workshop Agenda
Workshop Objectives
Mirjam Luitjen, RIVM
Path Forward for Genetic Toxicity Assessment
Kerry Dearfield, Former USDA
The New Strategy in Practice: Case Study Examples
Veronique Thybaud, Sanofi & Nicholas Ball, DOW
Incorporating Mode of Action into Genetic Toxicity Assessment
Roland Frötschl, BfArM, Germany
Novel Approaches and Technologies to Assess Genotoxic Modes of Action
Stefan Pfuhler, Procter & Gamble
Genetic Toxicity Mini-Adverse Outcome Pathways (mini-AOPs)
Azeddine Elhajouji, Novartis
Approaches for Analyses and Interpretation of Genetic Toxicity Dose-Response
Paul White, Health Canada
Quantitative Dose-Response Analyses for Risk Assessment and Regulatory Decision Making: Issues, Applications, and Challenges
George Johnson, Swansea University
Background and Objectives
Applied genetic toxicology is undergoing a major paradigm shift towards changing the strategies employed for assessment of chemically-induced genomic damage, evaluation methods of the mechanisms by which that damage translates into adverse effects, and the quantitative methods used to interpret dose-response data. This shift entails a movement away from simple dichotomous evaluations of genotoxicity (i.e., yes/no), that only supports identification of potential carcinogens, and towards a greater understanding of the diversity of adverse outcomes related to genomic damage, of the multitude of mechanisms (or modes of action) underscoring genomic damage, and the ability to determine point of departure metrics for human health risk assessment and regulatory decision making. Moreover, advanced technologies to investigate genotoxic mechanisms and to analyze dose-response functions are being developed and incorporated into assessments of genomic damage.
This workshop was organized by the HESI Genetic Toxicology Technical Committee (GTTC). The HESI GTTC brings together an international cohort of genetic toxicologists from industry, academia, and government to address issues related to all aspects of genetic toxicity assessment. These aspects include the development and validation of assessment approaches, technologies and strategies for mode-of-action determination, and approaches for data interpretation. The GTTC is comprised of experts in the fields of genetic and general toxicology, risk assessment, and computational biology. The workshop will examine a new generation of testing strategy for assessment of genomic damage, new approaches and technologies for mode-of-action determination and interpretation, and recent developments in quantitative interpretation of genetic toxicity dose-response data.
[post_title] => Applied Genetic Toxicity for Regulatory Decision Making: The Road Ahead
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => applied-genetic-toxicity-for-regulatory-decision-making-the-road-ahead
[to_ping] =>
[pinged] =>
[post_modified] => 2020-10-28 14:43:24
[post_modified_gmt] => 2020-10-28 14:43:24
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=6968
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
)
[post_count] => 6
[current_post] => -1
[before_loop] =>
[in_the_loop] =>
[post] => WP_Post Object
(
[ID] => 6586
[post_author] => 8
[post_date] => 2018-01-10 11:49:39
[post_date_gmt] => 2018-01-10 16:49:39
[post_content] =>
[post_title] => 2018 HESI Annual Meeting
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => 2018hesiannualmeeting
[to_ping] =>
[pinged] =>
[post_modified] => 2018-01-10 11:49:39
[post_modified_gmt] => 2018-01-10 16:49:39
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=event&p=6586
[menu_order] => 0
[post_type] => event
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[comment_count] => 0
[current_comment] => -1
[found_posts] => 13
[max_num_pages] => 3
[max_num_comment_pages] => 0
[is_single] =>
[is_preview] =>
[is_page] =>
[is_archive] =>
[is_date] =>
[is_year] =>
[is_month] =>
[is_day] =>
[is_time] =>
[is_author] =>
[is_category] =>
[is_tag] =>
[is_tax] =>
[is_search] =>
[is_feed] =>
[is_comment_feed] =>
[is_trackback] =>
[is_home] => 1
[is_privacy_policy] =>
[is_404] =>
[is_embed] =>
[is_paged] => 1
[is_admin] =>
[is_attachment] =>
[is_singular] =>
[is_robots] =>
[is_favicon] =>
[is_posts_page] =>
[is_post_type_archive] =>
[query_vars_hash:WP_Query:private] => 48da0a187cf56c9884ae9d1813fe6f61
[query_vars_changed:WP_Query:private] =>
[thumbnails_cached] =>
[allow_query_attachment_by_filename:protected] =>
[stopwords:WP_Query:private] =>
[compat_fields:WP_Query:private] => Array
(
[0] => query_vars_hash
[1] => query_vars_changed
)
[compat_methods:WP_Query:private] => Array
(
[0] => init_query_flags
[1] => parse_tax_query
)
)
hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-8403
740 15th Street NW, Suite 600
Washington, DC 20005
Sign up for our monthly e-newsletter.