Environmental Mutagenesis & Genomics Society 54th Annual Meeting

Several HESI programs will be featured throughout the meeting:

Botanical Safety Consortium Genotoxicity Technical Working Group

• Poster presentation: “A Strategy for Developing a Robust Framework of Genotoxicity Assays for Safety Assessment of Botanicals”

Genetic Toxicology Technical Committee

• 10 September 2023, 9:45am - 11:45am - Platform 1: Modern in vitro genetox screening and data modeling. “In Vitro-In Vivo Extrapolation (IVIVE) of Genetic Toxicity New Approach Methodology (NAM) Data: A HESI-GTTC Case Study” presented by Dr. Alexandra Long (Health Canada).
• 12 September 2023, 1:15 - 3:15pm - Platform 5:Don’t shoot the messenger: Mutant fraction and mutation frequency quantitation is biased by coverage depth in error-corrected sequencing studies, presented by: Meagan Myers, National Center for Toxicological Research/US FDA
•  13 September 2023, 1:15 - 3:15pm - Symposium 14: Ongoing validations of TGR tech transfer and bridging studies from TGR to ecNGS. Highlights GTTC’s ecNGS working group reconstruction experiment.

HESI CT-TRACS Committee

• 12 September 2023 - Full-day Session - Evaluating genotoxic potential of genome editing for therapeutic use. Presentation titled “Induce-Seq followed by Duplex-Seq for identification and confirmation of CRISPR-Cas9 off-targets- A HESI CT-TRACS supported project”.

View full meeting details here.