Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Rehm S, Solleveld HA, Portelli ST, Wier PJ
- HESI - Health and Environmental Sciences Institute
Idoxifene is a selective estrogen receptor modulator similar to tamoxifen but is no longer in pharmaceutical development due to adverse genitourinary effects in the clinic.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Rehm S, Stanislaus DJ, Wier PJ
- HESI - Health and Environmental Sciences Institute
Observations associated with drug-induced hyper- or hypoprolactinemia in rat toxicology studies may be similar and include increased ovarian weight due to increased presence of corpora lutea.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Rehm S, Stanislaus DJ, Williams AM
- HESI - Health and Environmental Sciences Institute
This report describes normal histology of tissues from immature female dogs and sequential microscopic changes that occur during different stages of the estrous cycle in ovary, uterus, vagina and mammary glands.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2006
Watson RE, DeSesso JM, Hurtt ME, Cappon GD
- HESI - Health and Environmental Sciences Institute
The objective of this report is to summarize the available literature regarding the postnatal growth and morphological development of the brain and compare the timelines for these events between humans and experimental species.
Toxicological Sciences, 2005
Ladics GS, Chapin RE, Hastings KL, Holsapple MP, Makris SL, ...
- HESI - Health and Environmental Sciences Institute
Developmental and reproductive toxicology (DART) has routinely been a part of safety assessment.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2005
Walthall K, Cappon GD, Hurtt ME, Zoetis T
- HESI - Health and Environmental Sciences Institute
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