Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
Filter

A Proposed Testing Framework for Developmental Immunotoxicology (DIT)

Toxicological Sciences, 2005

Holsapple MP, Burns-Naas LA, Hastings KL, Ladics GS, Lavin AL, ...
  • HESI - Health and Environmental Sciences Institute

A group of thirty immunotoxicology experts from the U.S. and E.U. representing government, industry, and academia met in May 2003, in Washington, D.C., to reach consensus regarding the most appropriate methods to assess developmental immunotoxicology (DIT) for hazard identification, including under what conditions such ...

Read more

A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium

International Journal of Toxicology, 2018

Emmanuel Boulay, Matthew M. Abernathy, Ray Chu, ...
  • HESI - Health and Environmental Sciences Institute

Results from this limited retrospective electrocardiogram analysis suggest that JTpca and Tpeca may discriminate selective IKr blockers and multichannel blockers and could be considered in the context of an integrated comprehensive proarrhythmic risk assessment.

Read more

A Multi-Laboratory Evaluation of a Common In Vitro Pepsin Digestion Assay Protocol Used in Assessing the Safety of Novel Proteins

Regulatory Toxicology and Pharmacology, 2004

Thomas K, Aalbers M, Bannon GA, Bartels M, Dearman RJ, Esdaile DJ, ...
  • HESI - Health and Environmental Sciences Institute

Evaluation of the potential allergenicity of proteins derived from genetically modified foods has involved a weight of evidence approach that incorporates an evaluation of protein digestibility in pepsin.

Read more

WP_Query Object
(
    [query] => Array
        (
            [post_type] => publication
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [committee] => 
            [authors] => true
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => AND
                )

            [tax_query] => Array
                (
                )

            [paged] => 77
            [orderby] => title
            [order] => DESC
        )

    [query_vars] => Array
        (
            [post_type] => publication
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [committee] => 
            [authors] => true
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => AND
                )

            [tax_query] => Array
                (
                )

            [paged] => 77
            [orderby] => title
            [order] => DESC
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [meta_key] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => 
            [menu_order] => 
            [embed] => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [search_columns] => Array
                (
                )

            [ignore_sticky_posts] => 
            [suppress_filters] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [update_menu_item_cache] => 
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [meta_table] => 
            [meta_id_column] => 
            [primary_table] => 
            [primary_id_column] => 
            [table_aliases:protected] => Array
                (
                )

            [clauses:protected] => Array
                (
                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => 
					SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					FROM wp_posts 
					WHERE 1=1  AND ((wp_posts.post_type = 'publication' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
					
					ORDER BY wp_posts.post_title DESC
					LIMIT 456, 6
				
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 2665
                    [post_author] => 6
                    [post_date] => 2016-05-10 08:18:58
                    [post_date_gmt] => 2016-05-10 13:18:58
                    [post_content] => 
                    [post_title] => A Public–Private Consortium Advances Cardiac Safety Evaluation: Achievements of the HESI Cardiac Safety Technical Committee
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-public-private-consortium-advances-cardiac-safety-evaluation-achievements-of-the-hesi-cardiac-safety-technical-committee
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-05-10 08:18:58
                    [post_modified_gmt] => 2016-05-10 13:18:58
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => http://ilsi.org/hesi/?post_type=publication&p=2665
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [1] => WP_Post Object
                (
                    [ID] => 3386
                    [post_author] => 6
                    [post_date] => 2016-06-26 22:29:09
                    [post_date_gmt] => 2016-06-27 03:29:09
                    [post_content] => 
                    [post_title] => A Proposed Testing Framework for Developmental Immunotoxicology (DIT)
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-proposed-testing-framework-for-developmental-immunotoxicology-dit
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-26 22:29:09
                    [post_modified_gmt] => 2016-06-27 03:29:09
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3386
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [2] => WP_Post Object
                (
                    [ID] => 3232
                    [post_author] => 6
                    [post_date] => 2016-06-17 23:57:31
                    [post_date_gmt] => 2016-06-18 04:57:31
                    [post_content] => 
                    [post_title] => A Proposed Framework for Assessing Risk From Less-Than-Lifetime Exposures to Carcinogens
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-proposed-framework-for-assessing-risk-from-less-than-lifetime-exposures-to-carcinogens
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-17 23:57:31
                    [post_modified_gmt] => 2016-06-18 04:57:31
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3232
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [3] => WP_Post Object
                (
                    [ID] => 20866
                    [post_author] => 2
                    [post_date] => 2019-01-17 15:34:48
                    [post_date_gmt] => 2019-01-17 20:34:48
                    [post_content] => 
                    [post_title] => A Proof-of-Concept Evaluation of JTPc and Tp-Tec as Proarrhythmia Biomarkers in Preclinical Species: A Retrospective Analysis by an HESI-Sponsored Consortium
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-proof-of-concept-evaluation-of-jtpc-and-tp-tec-as-proarrhythmia-biomarkers-in-preclinical-species-a-retrospective-analysis-by-an-hesi-sponsored-consortium
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2019-01-17 15:34:48
                    [post_modified_gmt] => 2019-01-17 20:34:48
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=20866
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [4] => WP_Post Object
                (
                    [ID] => 3429
                    [post_author] => 6
                    [post_date] => 2016-06-27 16:57:08
                    [post_date_gmt] => 2016-06-27 21:57:08
                    [post_content] => 
                    [post_title] => A Multi-Laboratory Evaluation of a Common In Vitro Pepsin Digestion Assay Protocol Used in Assessing the Safety of Novel Proteins
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-multi-laboratory-evaluation-of-a-common-in-vitro-pepsin-digestion-assay-protocol-used-in-assessing-the-safety-of-novel-proteins
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-27 16:57:08
                    [post_modified_gmt] => 2016-06-27 21:57:08
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3429
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [5] => WP_Post Object
                (
                    [ID] => 6980
                    [post_author] => 13
                    [post_date] => 2018-05-21 10:14:06
                    [post_date_gmt] => 2018-05-21 15:14:06
                    [post_content] => 
                    [post_title] => A multi-center preclinical study of gadoxetate DCE-MRI in rats as a biomarker of drug induced inhibition of liver transporter function
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-multi-center-preclinical-study-of-gadoxetate-dce-mri-in-rats-as-a-biomarker-of-drug-induced-inhibition-of-liver-transporter-function
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2018-05-21 10:14:06
                    [post_modified_gmt] => 2018-05-21 15:14:06
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=6980
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

        )

    [post_count] => 6
    [current_post] => -1
    [before_loop] => 
    [in_the_loop] => 
    [post] => WP_Post Object
        (
            [ID] => 2665
            [post_author] => 6
            [post_date] => 2016-05-10 08:18:58
            [post_date_gmt] => 2016-05-10 13:18:58
            [post_content] => 
            [post_title] => A Public–Private Consortium Advances Cardiac Safety Evaluation: Achievements of the HESI Cardiac Safety Technical Committee
            [post_excerpt] => 
            [post_status] => publish
            [comment_status] => closed
            [ping_status] => closed
            [post_password] => 
            [post_name] => a-public-private-consortium-advances-cardiac-safety-evaluation-achievements-of-the-hesi-cardiac-safety-technical-committee
            [to_ping] => 
            [pinged] => 
            [post_modified] => 2016-05-10 08:18:58
            [post_modified_gmt] => 2016-05-10 13:18:58
            [post_content_filtered] => 
            [post_parent] => 0
            [guid] => http://ilsi.org/hesi/?post_type=publication&p=2665
            [menu_order] => 0
            [post_type] => publication
            [post_mime_type] => 
            [comment_count] => 0
            [filter] => raw
        )

    [comment_count] => 0
    [current_comment] => -1
    [found_posts] => 476
    [max_num_pages] => 80
    [max_num_comment_pages] => 0
    [is_single] => 
    [is_preview] => 
    [is_page] => 
    [is_archive] => 
    [is_date] => 
    [is_year] => 
    [is_month] => 
    [is_day] => 
    [is_time] => 
    [is_author] => 
    [is_category] => 
    [is_tag] => 
    [is_tax] => 
    [is_search] => 
    [is_feed] => 
    [is_comment_feed] => 
    [is_trackback] => 
    [is_home] => 1
    [is_privacy_policy] => 
    [is_404] => 
    [is_embed] => 
    [is_paged] => 1
    [is_admin] => 
    [is_attachment] => 
    [is_singular] => 
    [is_robots] => 
    [is_favicon] => 
    [is_posts_page] => 
    [is_post_type_archive] => 
    [query_vars_hash:WP_Query:private] => d2564f87353e77b9d10304ea666d889e
    [query_vars_changed:WP_Query:private] => 
    [thumbnails_cached] => 
    [allow_query_attachment_by_filename:protected] => 
    [stopwords:WP_Query:private] => 
    [compat_fields:WP_Query:private] => Array
        (
            [0] => query_vars_hash
            [1] => query_vars_changed
        )

    [compat_methods:WP_Query:private] => Array
        (
            [0] => init_query_flags
            [1] => parse_tax_query
        )

)

Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-3859

740 15th Street NW, Suite 600
Washington, DC 20005

Stay Informed

Sign up for our monthly e-newsletter.