Journal of Pharmacological and Toxicological Methods, 2017
Michael K. Pugsley, Brian Guth, AlanY. Chiang, ...
- HESI - Health and Environmental Sciences Institute
The importance of drug-induced effects on the inotropic state of the heart is well known. Unlike hemodynamic and cardiac electrophysiological methods, which have been routinely used in drug safety testing for years, the non-clinical assessment of drug effects on myocardial contractility is used less frequently with ...
1997
...
- HESI - Health and Environmental Sciences Institute
This workshop report was published by HESI, Washington, DC.
Toxicologic Pathology, 2001
MacDonald J, Robinson DE, Pettit S (Editors)
- HESI - Health and Environmental Sciences Institute
To download an open-access PDF copy, click here.
Regulatory Toxicology and Pharmacology, 2020
Stanley T. Parish, Michael Aschner, Warren Casey, Marco Corvaro, ...
- HESI - Health and Environmental Sciences Institute
The need to develop new tools and increase capacity to test pharmaceuticals and other chemicals for potential adverse impacts on human health and the environment is an active area of development. The response to these challenges for a “paradigm shift” toward using new approach methodologies (NAMS) for safety assessment has ...
1999
ILSI Health and Environmental Sciences Institute
- HESI - Health and Environmental Sciences Institute
This workshop report was published by HESI, Washington, DC.
Critical Reviews in Toxicology, 2013
Scholz S, Renner P, Belanger SE, Busquet F, Davi R, Demeneix BA, ...
- HESI - Health and Environmental Sciences Institute
Endocrine disruption is considered a highly relevant hazard for environmental risk assessment of chemicals, plant protection products, biocides and pharmaceuticals.
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