Application of New Statistical Distribution Approaches for Environmental Mixture Risk Assessment: A Case Study

  • Publication Date :
  • Publication Type : Journal Article
  • Author(s) : Kienzler A, Bopp S, Halder M, Embry MR, Worth A
  • Journal Name : Science of the Total Environment

There is growing evidence that single substances present below their individual thresholds of effect may still contribute to combined effects. In component-based mixture risk assessment (MRA), the risks can be addressed using information on the mixture components. This is, however, often hampered by limited availability of ecotoxicity data. Here, the possible use of ecotoxicological threshold concentrations of no concern (i.e. 5th percentile of statistical distribution of ecotoxicological values) is investigated to fill data gaps in MRA.

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