Methapyrilene (MP) exposure of animals can result in an array of adverse pathological responses including hepatotoxicity.
Methapyrilene Toxicity: Anchorage of Pathologic Observations to Gene Expression Alterations
Toxicologic Pathology, 2002
Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.
Toxicologic Pathology, 2002
Methapyrilene (MP) exposure of animals can result in an array of adverse pathological responses including hepatotoxicity.
Human and Experimental Toxicology, 2002
Keliximab is a human-cynomolgus monkey chimeric (Primatized) monoclonal antibody with specificity for human and chimpanzee CD4.
Human and Experimental Toxicology, 2002
Identifying critical windows in immune system development is crucial for determination of either safety or vulnerability to exposure to specific agents during rapidly changing phases of ontogeny.
Human and Experimental Toxicology, 2002
Evidence is presented to demonstrate that the rat is a sensitive rodent species for developmental immunotoxicity testing of chemicals.
Human and Experimental Toxicology, 2002
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Human and Experimental Toxicology, 2002
There are many limitations to analyse the developing immune system in humans, thus there is need for experimental animal models to study the environmental influences during the ontogeny of the immune system.
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