Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Summary of a Workshop on Preclinical and Translational Safety Assessment of CD3 Bispecifics

Journal of Immunotoxicology, 2020

Kamperschroer C, Shenton J, Lebrec H, Leighton JK, Moore PA, ...

Currently, there is a multitude of CD3 bispecifics with different molecular designs and binding properties in preclinical and clinical development for the treatment of liquid or solid tumors. The key safety concerns with CD3 bispecifics are excessive release of cytokines, which may translate to potentially life-threating ...

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Summary of the HESI Consortium Studies Exploring Circulating Inhibin B as a Potential Biomarker of Testis Damage in the Rat

Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013

Chapin R, Weinbauer G, Thibodeau MS, Sonee M, Saldutti LP, ...
  • HESI - Health and Environmental Sciences Institute

The Developmental and Reproductive Toxicity Technical Committee of the Health and Environmental Sciences Institute hosted a working consortium of companies to evaluate a new commercially available analytic assay for Inhibin B in rat serum or plasma.

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Survey: Immune Function and Immunotoxicity Assessment in Dogs

Journal of Immunotoxicology, 2012

Lebrec H, O’Lone R, Freebern W, Komocsar W, Moore P
  • HESI - Health and Environmental Sciences Institute

While immunotoxicology evaluations are often conducted in either rodents or non-human primates, findings in standard toxicology studies may trigger additional investigations in dogs.

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Symposium Proceedings: Replacing the Draize Eye Irritation Test: Scientific Background and Research Needs Technical Committee on Alternatives to Animal Testing

Journal of Toxicology: Cutaneous and Ocular Toxicology, 1996

Neumann DA, ...
  • HESI - Health and Environmental Sciences Institute

Products in commerce, whether drugs, cosmetics, home and automobile care products, or bulk chemicals, are subject to a variety of tests to determine whether the ingredients and products have any potential adverse health effects.

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