Cardiovascular safety concerns are a significant cause of attrition in the development of new drugs (Lasser et al., 2002).
A Call for More Integrated Cardiovascular Safety Assessment
Journal of Pharmacological and Toxicological Methods, 2010
Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.
Journal of Pharmacological and Toxicological Methods, 2010
Cardiovascular safety concerns are a significant cause of attrition in the development of new drugs (Lasser et al., 2002).
Critical Reviews in Toxicology, 2014
The Health and Environmental Sciences Institute (HESI)-coordinated Risk Assessment in the 21st Century (RISK21) project was initiated to develop a scientific, transparent, and efficient approach to the evolving world of human health risk assessment, and involved over 120 participants from 12 countries, 15 government ...
Regulatory Toxicology and Pharmacology, 2024
This Commentary asserts that the challenges of realizing the systems-level changes needed to catalyze the broad-scale adoption and use of New Approach Methodologies (NAMs) may be less unique than perceived to date, and points to specific opportunities to learn from decades of experience (both positive and negative) from the ...
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