Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
Filter

A Different Approach to Validating Screening Assays for Developmental Toxicity

Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2010

Daston GP, Chapin RE, Scialli AR, Piersma AH, Carney EW, ...
  • HESI - Health and Environmental Sciences Institute

There continue to be many efforts around the world to develop assays that are shorter than the traditional embryofetal developmental toxicity assay, or use fewer or no mammals, or use less compound, or have all three attributes.

Read more

A Database of Fish Biotransformation Rates for Organic Chemicals

Environmental Toxicology and Chemistry, 2008

Arnot JA, Mackay D, Parkerton TF, Bonnell M
  • HESI - Health and Environmental Sciences Institute

Biotransformation is a key process that can mitigate the bioaccumulation potential of organic substances and is an important parameter for exposure assessments.

Read more

A Cross-Sector Call to Improve Carcinogenicity Risk Assessment Through Use of Genomic Methodologies

Regulatory Toxicology and Pharmacology, 2019

Yauk CL, Harrill AH, Ellinger-Ziegelbauer H, van der Laan JW, ...

Robust genomic approaches are now available to realize improvements in efficiencies and translational relevance of cancer risk assessments for drugs and chemicals. The authors propose a path for implementation of innovative cancer risk assessment including incorporating genomic signatures to assess mechanistic relevance ...

Read more

A Critical Review of Bioaccumulation and Biotransformation of Organic Chemicals in Birds

Reviews of Environmental Contamination and Toxicology, 2022

Kuo DTF, Rattner BA, Marteinson SC, Letcher R, Fernie KJ, Treu G, ...

A literature review of bioaccumulation and biotransformation of organic chemicals in birds was undertaken, aiming to support scoping and prioritization of future research. The objectives were to characterize available bioaccumulation/ biotransformation data, identify knowledge gaps, determine how extant data can be ...

Read more

A Comparison of Transgenic Rodent Mutation and In Vivo Comet Assay Responses for 91 Chemicals

Mutation Research / Genetic Toxicology and Environmental Mutagenesis, 2019

Kirkland D, Levy DD, LeBaron MJ, Aardema MJ, Beevers C, Bhalli J, ...

Whilst the TGR and comet assays are available for measuring genotoxic effects in multiple rodent tissues, there has been no systematic comparison of their performance in detecting genotoxicity per se. A working group of the Genetic Toxicology Technical Committee (GTTC), part of the Health and Environmental Sciences Institute ...

Read more

WP_Query Object
(
    [query] => Array
        (
            [post_type] => publication
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [committee] => 
            [authors] => true
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => AND
                )

            [tax_query] => Array
                (
                )

            [paged] => 79
            [orderby] => title
            [order] => DESC
        )

    [query_vars] => Array
        (
            [post_type] => publication
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [committee] => 
            [authors] => true
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => AND
                )

            [tax_query] => Array
                (
                )

            [paged] => 79
            [orderby] => title
            [order] => DESC
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [meta_key] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => 
            [menu_order] => 
            [embed] => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [search_columns] => Array
                (
                )

            [ignore_sticky_posts] => 
            [suppress_filters] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [update_menu_item_cache] => 
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [meta_table] => 
            [meta_id_column] => 
            [primary_table] => 
            [primary_id_column] => 
            [table_aliases:protected] => Array
                (
                )

            [clauses:protected] => Array
                (
                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => 
					SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					FROM wp_posts 
					WHERE 1=1  AND ((wp_posts.post_type = 'publication' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
					
					ORDER BY wp_posts.post_title DESC
					LIMIT 468, 6
				
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 3252
                    [post_author] => 6
                    [post_date] => 2016-06-20 11:23:46
                    [post_date_gmt] => 2016-06-20 16:23:46
                    [post_content] => 
                    [post_title] => A Different Approach to Validating Screening Assays for Developmental Toxicity
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-different-approach-to-validating-screening-assays-for-developmental-toxicity
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-20 11:23:46
                    [post_modified_gmt] => 2016-06-20 16:23:46
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3252
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [1] => WP_Post Object
                (
                    [ID] => 3301
                    [post_author] => 6
                    [post_date] => 2016-06-22 12:45:08
                    [post_date_gmt] => 2016-06-22 17:45:08
                    [post_content] => 
                    [post_title] => A Database of Fish Biotransformation Rates for Organic Chemicals
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-database-of-fish-biotransformation-rates-for-organic-chemicals
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-22 12:45:08
                    [post_modified_gmt] => 2016-06-22 17:45:08
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3301
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [2] => WP_Post Object
                (
                    [ID] => 3269
                    [post_author] => 6
                    [post_date] => 2016-06-20 22:27:04
                    [post_date_gmt] => 2016-06-21 03:27:04
                    [post_content] => 
                    [post_title] => A Data-Based Assessment of Alternative Strategies for Identification of Potential Human Cancer Hazards
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-data-based-assessment-of-alternative-strategies-for-identification-of-potential-human-cancer-hazards
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-20 22:27:04
                    [post_modified_gmt] => 2016-06-21 03:27:04
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3269
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [3] => WP_Post Object
                (
                    [ID] => 21992
                    [post_author] => 2
                    [post_date] => 2019-11-13 14:35:56
                    [post_date_gmt] => 2019-11-13 19:35:56
                    [post_content] => 
                    [post_title] => A Cross-Sector Call to Improve Carcinogenicity Risk Assessment Through Use of Genomic Methodologies
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-cross-sector-call-to-improve-carcinogenicity-risk-assessment-through-use-of-genomic-methodologies
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2020-10-28 14:28:33
                    [post_modified_gmt] => 2020-10-28 14:28:33
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=21992
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [4] => WP_Post Object
                (
                    [ID] => 25358
                    [post_author] => 16
                    [post_date] => 2022-05-24 14:59:01
                    [post_date_gmt] => 2022-05-24 14:59:01
                    [post_content] => 
                    [post_title] => A Critical Review of Bioaccumulation and Biotransformation of Organic Chemicals in Birds
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-critical-review-of-bioaccumulation-and-biotransformation-of-organic-chemicals-in-birds
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2022-05-24 14:59:35
                    [post_modified_gmt] => 2022-05-24 14:59:35
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=25358
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [5] => WP_Post Object
                (
                    [ID] => 21725
                    [post_author] => 2
                    [post_date] => 2019-09-06 12:50:25
                    [post_date_gmt] => 2019-09-06 17:50:25
                    [post_content] => 
                    [post_title] => A Comparison of Transgenic Rodent Mutation and In Vivo Comet Assay Responses for 91 Chemicals
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => a-comparison-of-transgenic-rodent-mutation-and-in-vivo-comet-assay-responses-for-91-chemicals
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2020-10-28 14:48:16
                    [post_modified_gmt] => 2020-10-28 14:48:16
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=21725
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

        )

    [post_count] => 6
    [current_post] => -1
    [before_loop] => 
    [in_the_loop] => 
    [post] => WP_Post Object
        (
            [ID] => 3252
            [post_author] => 6
            [post_date] => 2016-06-20 11:23:46
            [post_date_gmt] => 2016-06-20 16:23:46
            [post_content] => 
            [post_title] => A Different Approach to Validating Screening Assays for Developmental Toxicity
            [post_excerpt] => 
            [post_status] => publish
            [comment_status] => closed
            [ping_status] => closed
            [post_password] => 
            [post_name] => a-different-approach-to-validating-screening-assays-for-developmental-toxicity
            [to_ping] => 
            [pinged] => 
            [post_modified] => 2016-06-20 11:23:46
            [post_modified_gmt] => 2016-06-20 16:23:46
            [post_content_filtered] => 
            [post_parent] => 0
            [guid] => https://hesiglobal.org/?post_type=publication&p=3252
            [menu_order] => 0
            [post_type] => publication
            [post_mime_type] => 
            [comment_count] => 0
            [filter] => raw
        )

    [comment_count] => 0
    [current_comment] => -1
    [found_posts] => 479
    [max_num_pages] => 80
    [max_num_comment_pages] => 0
    [is_single] => 
    [is_preview] => 
    [is_page] => 
    [is_archive] => 
    [is_date] => 
    [is_year] => 
    [is_month] => 
    [is_day] => 
    [is_time] => 
    [is_author] => 
    [is_category] => 
    [is_tag] => 
    [is_tax] => 
    [is_search] => 
    [is_feed] => 
    [is_comment_feed] => 
    [is_trackback] => 
    [is_home] => 1
    [is_privacy_policy] => 
    [is_404] => 
    [is_embed] => 
    [is_paged] => 1
    [is_admin] => 
    [is_attachment] => 
    [is_singular] => 
    [is_robots] => 
    [is_favicon] => 
    [is_posts_page] => 
    [is_post_type_archive] => 
    [query_vars_hash:WP_Query:private] => 513ee99260c77d85a45a7ec62da83884
    [query_vars_changed:WP_Query:private] => 
    [thumbnails_cached] => 
    [allow_query_attachment_by_filename:protected] => 
    [stopwords:WP_Query:private] => 
    [compat_fields:WP_Query:private] => Array
        (
            [0] => query_vars_hash
            [1] => query_vars_changed
        )

    [compat_methods:WP_Query:private] => Array
        (
            [0] => init_query_flags
            [1] => parse_tax_query
        )

)

Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-3859

740 15th Street NW, Suite 600
Washington, DC 20005

Stay Informed

Sign up for our monthly e-newsletter.