Current Protocols in Toxicology, 2012
Johanning K, Hancock G, Escher B, Adekola A, Bernhard MJ, ...
- HESI - Health and Environmental Sciences Institute
Standard protocols are given for assessing metabolic stability in rainbow trout using the liver S9 fraction.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2013
Moffit JS, Her LS, Mineo AM, Knight BL, Phillips JA, Thibodeau MS
- HESI - Health and Environmental Sciences Institute
Although histopathology is considered the gold standard for assessing testicular toxicity in the nonclinical setting, identification of noninvasive biomarkers for testicular injury are desirable to improve safety monitoring capabilities for clinical trials.
Reproductive Toxicology, 2014
Breslin WJ, Hilbish KG, Page TJ, Coutant DE
- HESI - Health and Environmental Sciences Institute
Studies were conducted in New Zealand White rabbits to assess the seminal transfer, vaginal absorption, and placental transfer of a therapeutic monoclonal antibody (T-IgG4).
Reproductive Toxicology, 2015
Thompson KE, Rayhon SL, Bailey G, Delille P, McNerney ME
- HESI - Health and Environmental Sciences Institute
Risk assessment for indirect exposure to small molecule pharmaceuticals in semen to the conceptus has traditionally been handled by calculations based on assumptions that any embryo-fetal exposure would be secondary to maternal absorption and redistribution.
Toxicological Sciences, 2006
Holsapple MP, Jones D, Kawabata TT, Kimber I, Sarlo K, ...
- HESI - Health and Environmental Sciences Institute
Acute and repeat dose inhalation studies have been an important part of the safety assessment of drugs, chemicals, and other products throughout the world for many years.
Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2007
Cline JM
- HESI - Health and Environmental Sciences Institute
This review provides a summary of the normal biology, development, and morphology of the breast in nonhuman primates (macaques), and of the major published work addressing hormonally-induced changes in the breast of these animals.
WP_Query Object
(
[query] => Array
(
[post_type] => publication
[posts_per_page] => 6
[type] =>
[area] =>
[committee] =>
[authors] => true
[showtitle] => false
[meta_query] => Array
(
[relation] => AND
)
[tax_query] => Array
(
)
[paged] => 68
[orderby] => title
[order] => DESC
)
[query_vars] => Array
(
[post_type] => publication
[posts_per_page] => 6
[type] =>
[area] =>
[committee] =>
[authors] => true
[showtitle] => false
[meta_query] => Array
(
[relation] => AND
)
[tax_query] => Array
(
)
[paged] => 68
[orderby] => title
[order] => DESC
[error] =>
[m] =>
[p] => 0
[post_parent] =>
[subpost] =>
[subpost_id] =>
[attachment] =>
[attachment_id] => 0
[name] =>
[pagename] =>
[page_id] => 0
[second] =>
[minute] =>
[hour] =>
[day] => 0
[monthnum] => 0
[year] => 0
[w] => 0
[category_name] =>
[tag] =>
[cat] =>
[tag_id] =>
[author] =>
[author_name] =>
[feed] =>
[tb] =>
[meta_key] =>
[meta_value] =>
[preview] =>
[s] =>
[sentence] =>
[title] =>
[fields] =>
[menu_order] =>
[embed] =>
[category__in] => Array
(
)
[category__not_in] => Array
(
)
[category__and] => Array
(
)
[post__in] => Array
(
)
[post__not_in] => Array
(
)
[post_name__in] => Array
(
)
[tag__in] => Array
(
)
[tag__not_in] => Array
(
)
[tag__and] => Array
(
)
[tag_slug__in] => Array
(
)
[tag_slug__and] => Array
(
)
[post_parent__in] => Array
(
)
[post_parent__not_in] => Array
(
)
[author__in] => Array
(
)
[author__not_in] => Array
(
)
[search_columns] => Array
(
)
[ignore_sticky_posts] =>
[suppress_filters] =>
[cache_results] => 1
[update_post_term_cache] => 1
[update_menu_item_cache] =>
[lazy_load_term_meta] => 1
[update_post_meta_cache] => 1
[nopaging] =>
[comments_per_page] => 50
[no_found_rows] =>
)
[tax_query] => WP_Tax_Query Object
(
[queries] => Array
(
)
[relation] => AND
[table_aliases:protected] => Array
(
)
[queried_terms] => Array
(
)
[primary_table] => wp_posts
[primary_id_column] => ID
)
[meta_query] => WP_Meta_Query Object
(
[queries] => Array
(
)
[relation] => AND
[meta_table] =>
[meta_id_column] =>
[primary_table] =>
[primary_id_column] =>
[table_aliases:protected] => Array
(
)
[clauses:protected] => Array
(
)
[has_or_relation:protected] =>
)
[date_query] =>
[request] =>
SELECT SQL_CALC_FOUND_ROWS wp_posts.ID
FROM wp_posts
WHERE 1=1 AND ((wp_posts.post_type = 'publication' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
ORDER BY wp_posts.post_title DESC
LIMIT 402, 6
[posts] => Array
(
[0] => WP_Post Object
(
[ID] => 3213
[post_author] => 6
[post_date] => 2016-06-17 14:04:28
[post_date_gmt] => 2016-06-17 19:04:28
[post_content] =>
[post_title] => Assessment of Metabolic Stability Using the Rainbow Trout (Oncorhynchus mykiss) Liver S9 Fraction
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessment-of-metabolic-stability-using-the-rainbow-trout-oncorhynchus-mykiss-liver-s9-fraction
[to_ping] =>
[pinged] =>
[post_modified] => 2016-06-17 14:04:28
[post_modified_gmt] => 2016-06-17 19:04:28
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=publication&p=3213
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[1] => WP_Post Object
(
[ID] => 2682
[post_author] => 6
[post_date] => 2016-05-10 09:33:19
[post_date_gmt] => 2016-05-10 14:33:19
[post_content] =>
[post_title] => Assessment of Inhibin B as a Biomarker of Testicular Injury Following Administration of Carbendazim, Cetrorelix, or 1, 2‐Dibromo‐3‐Chloropropane in Wistar Han Rats
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessment-of-inhibin-b-as-a-biomarker-of-testicular-injury-following-administration-of-carbendazim-cetrorelix-or-1-2%e2%80%90dibromo%e2%80%903%e2%80%90chloropropane-in-wistar-han-rats
[to_ping] =>
[pinged] =>
[post_modified] => 2016-05-10 09:33:19
[post_modified_gmt] => 2016-05-10 14:33:19
[post_content_filtered] =>
[post_parent] => 0
[guid] => http://ilsi.org/hesi/?post_type=publication&p=2682
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[2] => WP_Post Object
(
[ID] => 2582
[post_author] => 6
[post_date] => 2016-05-04 20:23:55
[post_date_gmt] => 2016-05-05 01:23:55
[post_content] =>
[post_title] => Assessment of Fetal Exposure Risk Following Seminal Excretion of a Therapeutic IgG4 (T-IgG4) Monoclonal Antibody Using a Rabbit Model
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessment-of-fetal-exposure-risk-following-seminal-excretion-of-a-therapeutic-igg4-t-igg4-monoclonal-antibody-using-a-rabbit-model
[to_ping] =>
[pinged] =>
[post_modified] => 2016-05-04 20:23:55
[post_modified_gmt] => 2016-05-05 01:23:55
[post_content_filtered] =>
[post_parent] => 0
[guid] => http://ilsi.org/hesi/?post_type=publication&p=2582
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[3] => WP_Post Object
(
[ID] => 1978
[post_author] => 6
[post_date] => 2016-04-17 21:50:38
[post_date_gmt] => 2016-04-18 02:50:38
[post_content] =>
[post_title] => Assessment of Cervical Passage of Vital Dyes in Pregnant, Nonpregnant, and Mated Rat and Mice
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessment-of-cervical-passage-of-vital-dyes-in-pregnant-nonpregnant-and-mated-rat-and-mice
[to_ping] =>
[pinged] =>
[post_modified] => 2016-04-17 21:50:38
[post_modified_gmt] => 2016-04-18 02:50:38
[post_content_filtered] =>
[post_parent] => 0
[guid] => http://ilsi.org/hesi/?post_type=publication&p=1978
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[4] => WP_Post Object
(
[ID] => 3367
[post_author] => 6
[post_date] => 2016-06-26 21:17:44
[post_date_gmt] => 2016-06-27 02:17:44
[post_content] =>
[post_title] => Assessing the Potential to Induce Respiratory Hypersensitivity
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessing-the-potential-to-induce-respiratory-hypersensitivity
[to_ping] =>
[pinged] =>
[post_modified] => 2016-06-26 21:17:44
[post_modified_gmt] => 2016-06-27 02:17:44
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=publication&p=3367
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[5] => WP_Post Object
(
[ID] => 3323
[post_author] => 6
[post_date] => 2016-06-26 19:09:59
[post_date_gmt] => 2016-06-27 00:09:59
[post_content] =>
[post_title] => Assessing the Mammary Gland of Nonhuman Primates: Effects of Endogenous Hormones and Exogenous Hormonal Agents and Growth Factors
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessing-the-mammary-gland-of-nonhuman-primates-effects-of-endogenous-hormones-and-exogenous-hormonal-agents-and-growth-factors
[to_ping] =>
[pinged] =>
[post_modified] => 2016-06-26 19:09:59
[post_modified_gmt] => 2016-06-27 00:09:59
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=publication&p=3323
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
)
[post_count] => 6
[current_post] => -1
[before_loop] =>
[in_the_loop] =>
[post] => WP_Post Object
(
[ID] => 3213
[post_author] => 6
[post_date] => 2016-06-17 14:04:28
[post_date_gmt] => 2016-06-17 19:04:28
[post_content] =>
[post_title] => Assessment of Metabolic Stability Using the Rainbow Trout (Oncorhynchus mykiss) Liver S9 Fraction
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => assessment-of-metabolic-stability-using-the-rainbow-trout-oncorhynchus-mykiss-liver-s9-fraction
[to_ping] =>
[pinged] =>
[post_modified] => 2016-06-17 14:04:28
[post_modified_gmt] => 2016-06-17 19:04:28
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://hesiglobal.org/?post_type=publication&p=3213
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[comment_count] => 0
[current_comment] => -1
[found_posts] => 475
[max_num_pages] => 80
[max_num_comment_pages] => 0
[is_single] =>
[is_preview] =>
[is_page] =>
[is_archive] =>
[is_date] =>
[is_year] =>
[is_month] =>
[is_day] =>
[is_time] =>
[is_author] =>
[is_category] =>
[is_tag] =>
[is_tax] =>
[is_search] =>
[is_feed] =>
[is_comment_feed] =>
[is_trackback] =>
[is_home] => 1
[is_privacy_policy] =>
[is_404] =>
[is_embed] =>
[is_paged] => 1
[is_admin] =>
[is_attachment] =>
[is_singular] =>
[is_robots] =>
[is_favicon] =>
[is_posts_page] =>
[is_post_type_archive] =>
[query_vars_hash:WP_Query:private] => 2049316a622a4b21e75164c4f4de6c40
[query_vars_changed:WP_Query:private] =>
[thumbnails_cached] =>
[allow_query_attachment_by_filename:protected] =>
[stopwords:WP_Query:private] =>
[compat_fields:WP_Query:private] => Array
(
[0] => query_vars_hash
[1] => query_vars_changed
)
[compat_methods:WP_Query:private] => Array
(
[0] => init_query_flags
[1] => parse_tax_query
)
)
