N-phenylanthranilic acid is a chloride channel blocker that causes renal papillary necrosis in rats.
Biomarkers of Collecting Duct Injury in Han-Wistar and Sprague-Dawley Rats Treated With N-Phenylanthranilic Acid
Toxicologic Pathology, 2012
Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.
Toxicologic Pathology, 2012
N-phenylanthranilic acid is a chloride channel blocker that causes renal papillary necrosis in rats.
Toxicological Sciences, 2011
This study reports the evaluation of four urinary biomarkers of renal toxicity, α-glutathione-S-transferase (α-GST), μ-GST, clusterin, and renal papillary antigen-1 (RPA-1), in male Sprague-Dawley and Han-Wistar rats given cisplatin, gentamicin, or N-phenylanthranilic acid (NPAA).
Integrated Environmental Assessment and Management, 2012
Once they are released into the environment, a number of chemicals are known to bioaccumulate in organisms, sometimes to concentrations that may threaten the individual or their predators.
Clinical Pharmacology & Therapeutics, 2024
We are thrilled to announce the publication of a groundbreaking white paper by the HESI Immuno-Safety Technical Committee, now available in Clinical Pharmacology & Therapeutics.
Journal of Water Supply: Research and Technology–AQUA, 1994
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Journal of Water Supply: Research and Technology–AQUA, 1994
To view the full citation, click here.
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