Critical Reviews in Toxicology, 2006
Barton HA, Pastoor TP, Baetcke K, Chambers JE, Diliberto J, ...
- HESI - Health and Environmental Sciences Institute
A proposal has been developed by the Agricultural Chemical Safety Assessment (ACSA) Technical Committee of the ILSI Health and Environmental Sciences Institute (HESI) for an improved approach to assessing the safety of crop protection chemicals.
Environmental Health Perspectives, 2006
Butenhoff JL, Olsen GW, Pfahles-Hutchens A
- HESI - Health and Environmental Sciences Institute
Perfluorooctanesulfonate and its salts (PFOS) are derived from perfluorooctanesulfonyl fluoride, the basic chemical building block for many sulfonyl-based fluorochemicals used as surfactants and for their repellent properties.
Disease Models & Mechanisms, 2022
Sarah Campion, Amy Inselman, Belinda Hayes, Costanza Casiraghi, ...
Increased research to improve preclinical models to inform the development of therapeutics for neonatal diseases is an area of great need. This article reviews five common neonatal diseases – bronchopulmonary dysplasia, retinopathy of prematurity, necrotizing enterocolitis, perinatal hypoxic–ischemic ...
Regulatory Toxicology and Pharmacology, 2021
Mitchell CA, Dever JT, Gafner S, Griffiths JC, Marsman DS, ...
This commentary details the structure, goals, and strategies of the BSC and insights regarding our objectives, namely the selection and prioritization of botanicals based on putative toxicological properties.
Toxicological Sciences, 2022
Jean-Pierre Valentin, Peter Hoffmann, Catherine Ortemann-Renon, ...
New publication in Toxicological Sciences by the HESI Cardiac Safety Committee shows that nonclinical models used to predict cardiac safety during drug development do not absolutely replicate the clinical conditions; however, best practices can be used to improve the nonclinical assay quality and achieve the ...
Frontiers in Allergy, 2021
van Ree R, Ballerda DS, Berin MC, Beuf L, Chang A, Gadermaier G, ...
The availability of databases identifying allergenic proteins via a transparent and consensus-based scientific approach is of prime importance to support the safety review of genetically-modified foods and feeds, and public safety in general. Over recent years, screening for potential new allergens sequences has become ...
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