Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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TCDD-Mediated Suppression of the In Vitro Anti-Sheep Erythrocyte IgM Antibody Forming Cell Response Is Reversed by Interferon-Gamma

Toxicological Sciences, 2009

North CM, Kim BS, Snyder N, Crawford RB, Holsapple MP, ...
  • HESI - Health and Environmental Sciences Institute

Suppression of humoral immune responses by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been well established to require the aryl hydrocarbon receptor; however, the downstream mechanisms for this immunotoxic response remain poorly understood.

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Current Challenges in the Evaluation of Cardiac Safety During Drug Development: Translational Medicine Meets the Critical Path Initiative

American Heart Journal, 2009

Piccini JP, Whellan DJ, Berridge BR, Finkle JK, Pettit SD, ...
  • HESI - Health and Environmental Sciences Institute

In October 2008, in a public forum organized by the Cardiac Safety Research Consortium and the Health and Environmental Sciences Institute, leaders from government, the pharmaceutical industry, and academia convened in Bethesda, MD, to discuss current challenges in evaluation of short- and long-term cardiovascular safety ...

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The State of In Vitro Science for Use in Bioaccumulation Assessments for Fish

Environmental Toxicology and Chemistry, 2009

Weisbrod AV, Sahi J, Segner H, James MO, Nichols J, Schultz I, ...
  • HESI - Health and Environmental Sciences Institute

Through the concerted evaluations of thousands of commercial substances for the qualities of persistence, bioaccumulation, and toxicity as a result of the United Nations Environment Program's Stockholm Convention, it has become apparent that fewer empirical data are available on bioaccumulation than other endpoints and ...

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Health and Environmental Sciences Institute (HESI)

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