Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
Filter

Micro-CT Imaging: Developing Criteria for Examining Fetal Skeletons in Regulatory Developmental Toxicology Studies – A Workshop Report

Regulatory Toxicology and Pharmacology, 2016

Solomon HM, Makris SL, Alsaid H, Bermudez O, Beyer BK, Chen A, ...
  • HESI - Health and Environmental Sciences Institute

During the past two decades the use and refinements of imaging modalities have markedly increased making it possible to image embryos and fetuses used in pivotal nonclinical studies submitted to regulatory agencies.

Read more

Mode of Action (MOA) Classifications in the EnviroTox Database: Development and Implementation of a Consensus MOA Classification

Environmental Toxicology and Chemistry, 2019

Kienzler A, Connors KA, Bonnell M, Barron MG, Beasley A, ...

Multiple modes of action (MOA) frameworks have been developed in aquatic ecotoxicology, mainly based on fish toxicity. These frameworks provide information on a key determinant of chemical toxicity, but the MOA categories and level of specificity remain unique to each of the classification schemes. This study aimed to develop a ...

Read more

Mode of Action in Relevance of Rodent Liver Tumors to Human Cancer Risk

Toxicological Sciences, 2006

Holsapple MP, Pitot HC, Cohen SH, Boobis AR, Klaunig JE, ...
  • HESI - Health and Environmental Sciences Institute

Hazard identification and risk assessment paradigms depend on the presumption of the similarity of rodents to humans, yet species specific responses, and the extrapolation of high-dose effects to low-dose exposures can affect the estimation of human risk from rodent data.

Read more

WP_Query Object
(
    [query] => Array
        (
            [post_type] => publication
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [committee] => 
            [authors] => true
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => AND
                )

            [tax_query] => Array
                (
                )

            [paged] => 49
            [orderby] => title
            [order] => ASC
        )

    [query_vars] => Array
        (
            [post_type] => publication
            [posts_per_page] => 6
            [type] => 
            [area] => 
            [committee] => 
            [authors] => true
            [showtitle] => false
            [meta_query] => Array
                (
                    [relation] => AND
                )

            [tax_query] => Array
                (
                )

            [paged] => 49
            [orderby] => title
            [order] => ASC
            [error] => 
            [m] => 
            [p] => 0
            [post_parent] => 
            [subpost] => 
            [subpost_id] => 
            [attachment] => 
            [attachment_id] => 0
            [name] => 
            [pagename] => 
            [page_id] => 0
            [second] => 
            [minute] => 
            [hour] => 
            [day] => 0
            [monthnum] => 0
            [year] => 0
            [w] => 0
            [category_name] => 
            [tag] => 
            [cat] => 
            [tag_id] => 
            [author] => 
            [author_name] => 
            [feed] => 
            [tb] => 
            [meta_key] => 
            [meta_value] => 
            [preview] => 
            [s] => 
            [sentence] => 
            [title] => 
            [fields] => 
            [menu_order] => 
            [embed] => 
            [category__in] => Array
                (
                )

            [category__not_in] => Array
                (
                )

            [category__and] => Array
                (
                )

            [post__in] => Array
                (
                )

            [post__not_in] => Array
                (
                )

            [post_name__in] => Array
                (
                )

            [tag__in] => Array
                (
                )

            [tag__not_in] => Array
                (
                )

            [tag__and] => Array
                (
                )

            [tag_slug__in] => Array
                (
                )

            [tag_slug__and] => Array
                (
                )

            [post_parent__in] => Array
                (
                )

            [post_parent__not_in] => Array
                (
                )

            [author__in] => Array
                (
                )

            [author__not_in] => Array
                (
                )

            [search_columns] => Array
                (
                )

            [ignore_sticky_posts] => 
            [suppress_filters] => 
            [cache_results] => 1
            [update_post_term_cache] => 1
            [update_menu_item_cache] => 
            [lazy_load_term_meta] => 1
            [update_post_meta_cache] => 1
            [nopaging] => 
            [comments_per_page] => 50
            [no_found_rows] => 
        )

    [tax_query] => WP_Tax_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [table_aliases:protected] => Array
                (
                )

            [queried_terms] => Array
                (
                )

            [primary_table] => wp_posts
            [primary_id_column] => ID
        )

    [meta_query] => WP_Meta_Query Object
        (
            [queries] => Array
                (
                )

            [relation] => AND
            [meta_table] => 
            [meta_id_column] => 
            [primary_table] => 
            [primary_id_column] => 
            [table_aliases:protected] => Array
                (
                )

            [clauses:protected] => Array
                (
                )

            [has_or_relation:protected] => 
        )

    [date_query] => 
    [request] => 
					SELECT SQL_CALC_FOUND_ROWS  wp_posts.ID
					FROM wp_posts 
					WHERE 1=1  AND ((wp_posts.post_type = 'publication' AND (wp_posts.post_status = 'publish' OR wp_posts.post_status = 'acf-disabled')))
					
					ORDER BY wp_posts.post_title ASC
					LIMIT 288, 6
				
    [posts] => Array
        (
            [0] => WP_Post Object
                (
                    [ID] => 3327
                    [post_author] => 6
                    [post_date] => 2016-06-26 19:55:58
                    [post_date_gmt] => 2016-06-27 00:55:58
                    [post_content] => 
                    [post_title] => Methodologies for Developmental Immunotoxicity (DIT) Testing
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => methodologies-for-developmental-immunotoxicity-dit-testing
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-26 19:55:58
                    [post_modified_gmt] => 2016-06-27 00:55:58
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3327
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [1] => WP_Post Object
                (
                    [ID] => 1940
                    [post_author] => 6
                    [post_date] => 2016-04-17 21:55:22
                    [post_date_gmt] => 2016-04-18 02:55:22
                    [post_content] => 
                    [post_title] => Micro-CT Imaging: Developing Criteria for Examining Fetal Skeletons in Regulatory Developmental Toxicology Studies – A Workshop Report
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => micro-ct-imaging-developing-criteria-for-examining-fetal-skeletons-in-regulatory-developmental-toxicology-studies-a-workshop-report
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-04-17 21:55:22
                    [post_modified_gmt] => 2016-04-18 02:55:22
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => http://ilsi.org/hesi/?post_type=publication&p=1940
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [2] => WP_Post Object
                (
                    [ID] => 2586
                    [post_author] => 6
                    [post_date] => 2016-05-04 20:23:32
                    [post_date_gmt] => 2016-05-05 01:23:32
                    [post_content] => 
                    [post_title] => MicroRNA-34c-3p Is an Early Predictive Biomarker for Doxorubicin-Induced Glomerular Injury Progression in Male Sprague-Dawley Rats
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => microrna-34c-3p-is-an-early-predictive-biomarker-for-doxorubicin-induced-glomerular-injury-progression-in-male-sprague-dawley-rats
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-05-04 20:23:32
                    [post_modified_gmt] => 2016-05-05 01:23:32
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => http://ilsi.org/hesi/?post_type=publication&p=2586
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [3] => WP_Post Object
                (
                    [ID] => 1983
                    [post_author] => 6
                    [post_date] => 2016-04-17 21:38:50
                    [post_date_gmt] => 2016-04-18 02:38:50
                    [post_content] => 
                    [post_title] => Mining the Archives: A Cross-Platform Analysis of Gene Expression Profiles in Archival Formalin-Fixed Paraffin-Embedded (FFPE) Tissue
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => mining-the-archives-a-cross-platform-analysis-of-gene-expression-profiles-in-archival-formalin-fixed-paraffin-embedded-ffpe-tissue
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-04-17 21:38:50
                    [post_modified_gmt] => 2016-04-18 02:38:50
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => http://ilsi.org/hesi/?post_type=publication&p=1983
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [4] => WP_Post Object
                (
                    [ID] => 21517
                    [post_author] => 2
                    [post_date] => 2019-08-01 08:31:01
                    [post_date_gmt] => 2019-08-01 13:31:01
                    [post_content] => 
                    [post_title] => Mode of Action (MOA) Classifications in the EnviroTox Database: Development and Implementation of a Consensus MOA Classification
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => mode-of-action-moa-classifications-in-the-envirotox-database-development-and-implementation-of-a-consensus-moa-classification
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2020-10-28 13:22:03
                    [post_modified_gmt] => 2020-10-28 13:22:03
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=21517
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

            [5] => WP_Post Object
                (
                    [ID] => 3368
                    [post_author] => 6
                    [post_date] => 2016-06-26 21:17:55
                    [post_date_gmt] => 2016-06-27 02:17:55
                    [post_content] => 
                    [post_title] => Mode of Action in Relevance of Rodent Liver Tumors to Human Cancer Risk
                    [post_excerpt] => 
                    [post_status] => publish
                    [comment_status] => closed
                    [ping_status] => closed
                    [post_password] => 
                    [post_name] => mode-of-action-in-relevance-of-rodent-liver-tumors-to-human-cancer-risk
                    [to_ping] => 
                    [pinged] => 
                    [post_modified] => 2016-06-26 21:17:55
                    [post_modified_gmt] => 2016-06-27 02:17:55
                    [post_content_filtered] => 
                    [post_parent] => 0
                    [guid] => https://hesiglobal.org/?post_type=publication&p=3368
                    [menu_order] => 0
                    [post_type] => publication
                    [post_mime_type] => 
                    [comment_count] => 0
                    [filter] => raw
                )

        )

    [post_count] => 6
    [current_post] => -1
    [before_loop] => 
    [in_the_loop] => 
    [post] => WP_Post Object
        (
            [ID] => 3327
            [post_author] => 6
            [post_date] => 2016-06-26 19:55:58
            [post_date_gmt] => 2016-06-27 00:55:58
            [post_content] => 
            [post_title] => Methodologies for Developmental Immunotoxicity (DIT) Testing
            [post_excerpt] => 
            [post_status] => publish
            [comment_status] => closed
            [ping_status] => closed
            [post_password] => 
            [post_name] => methodologies-for-developmental-immunotoxicity-dit-testing
            [to_ping] => 
            [pinged] => 
            [post_modified] => 2016-06-26 19:55:58
            [post_modified_gmt] => 2016-06-27 00:55:58
            [post_content_filtered] => 
            [post_parent] => 0
            [guid] => https://hesiglobal.org/?post_type=publication&p=3327
            [menu_order] => 0
            [post_type] => publication
            [post_mime_type] => 
            [comment_count] => 0
            [filter] => raw
        )

    [comment_count] => 0
    [current_comment] => -1
    [found_posts] => 479
    [max_num_pages] => 80
    [max_num_comment_pages] => 0
    [is_single] => 
    [is_preview] => 
    [is_page] => 
    [is_archive] => 
    [is_date] => 
    [is_year] => 
    [is_month] => 
    [is_day] => 
    [is_time] => 
    [is_author] => 
    [is_category] => 
    [is_tag] => 
    [is_tax] => 
    [is_search] => 
    [is_feed] => 
    [is_comment_feed] => 
    [is_trackback] => 
    [is_home] => 1
    [is_privacy_policy] => 
    [is_404] => 
    [is_embed] => 
    [is_paged] => 1
    [is_admin] => 
    [is_attachment] => 
    [is_singular] => 
    [is_robots] => 
    [is_favicon] => 
    [is_posts_page] => 
    [is_post_type_archive] => 
    [query_vars_hash:WP_Query:private] => be146fbf65118ee83029ac5f713a57ca
    [query_vars_changed:WP_Query:private] => 
    [thumbnails_cached] => 
    [allow_query_attachment_by_filename:protected] => 
    [stopwords:WP_Query:private] => 
    [compat_fields:WP_Query:private] => Array
        (
            [0] => query_vars_hash
            [1] => query_vars_changed
        )

    [compat_methods:WP_Query:private] => Array
        (
            [0] => init_query_flags
            [1] => parse_tax_query
        )

)

Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-3859

740 15th Street NW, Suite 600
Washington, DC 20005

Stay Informed

Sign up for our monthly e-newsletter.