Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Integration of Metabolic Activation With a Predictive Toxicogenomics Signature to Classify Genotoxic Versus Nongenotoxic Chemicals in Human TK6 Cells

Environmental and Molecular Mutagenesis, 2015

Buick JK, Moffat I, Williams A, Swartz CD, Recio L, Hyduke DR, ...
  • HESI - Health and Environmental Sciences Institute

The use of integrated approaches in genetic toxicology, including the incorporation of gene expression data to determine the molecular pathways involved in the response, is becoming more common.

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Inter-Laboratory Optimization of Protein Extraction, Separation, and Fluorescent Detection of Endogenous Rice Allergens

Bioscience, Biotechnology, Biochemistry, 2016

Satoh R, Teshima R, Kitta K, Lang GH, Schegg K, Blumenthal K, ...

In rice, several allergens have been identified such as the non-specific lipid transfer protein-1, the α-amylase/trypsin-inhibitors, the α-globulin, the 33 kDa glyoxalase I (Gly I), the 52–63 kDa globulin, and the granule-bound starch synthetase. The goal of the present study was to define optimal rice extraction and ...

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Interlaboratory Study of the Primary Antibody Response to Sheep Red Blood Cells in Outbred Rodents Following Exposure to Cyclophosphamide or Dexamethasone

Journal of Immunotoxicology, 2007

Loveless SE, Ladics GS, Smith C, Holsapple MP, Woolhiser MR, ...
  • HESI - Health and Environmental Sciences Institute

EPA guidelines provide a choice in evaluating humoral immune system function in rats and mice immunized with sheep red blood cells (sRBC): an antibody-forming cell (AFC) assay or a sRBC-specific serum IgM enzyme-linked immunosorbent assay (ELISA).

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International evaluation study of a highly efficient culture assay for detection of residual human pluripotent stem cells in cell therapies

Regenerative Medicine, 2023

Takeshi Watanabe, Satoshi Yasuda, Connie L Chen, Louise Delsing, ...

HESI’s Cell Therapy-TRAcking, Circulation & Safety Technical Committee completed an international, multisite study to evaluate the sensitivity and reproducibility of the highly efficient culture (HEC) assay, an in vitro assay to detect residual undifferentiated human pluripotent stem cells (hPSCs) in cell therapy ...

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Health and Environmental Sciences Institute (HESI)

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