Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Explaining Differences Between Bioaccumulation Measurements in Laboratory and Field Data Through Use of a Probabilistic Modeling Approach

In the regulatory context, bioaccumulation assessment is often hampered by substantial data uncertainty as well as by the poorly understood differences often observed between results from laboratory and field bioaccumulation studies.

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The Value of Juvenile Animal Studies “What Have We Learned From Preclinical Juvenile Toxicity Studies? II”

Recent changes in the regulations from the FDA and EMA have shifted the focus of juvenile toxicity studies more to the safe use of all pharmaceuticals and the absence of label or safety information for the pediatric population.

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Risk Assessment of Combined Exposure to Multiple Chemicals: A WHO/IPCS Framework, Annex B Example Case Study B: Tier 0 – Substances Potentially Detectable in Surface Water

This paper describes a framework for the risk assessment of combined exposure to multiple chemicals based on and developed subsequent to the World Health Organization/International Programme on Chemical Safety Workshop on Aggregate/Cumulative Risk Assessment (Combined Exposures to Multiple Chemicals) held in 2007.

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