Environmental Toxicology and Chemistry, 2014
Villeneuve D, Volz DC, Embry MR, Ankley GT, Belanger SE, ...
- HESI - Health and Environmental Sciences Institute
The fish early-life stage (FELS) test (Organisation for Economic Co-operation and Development [OECD] test guideline 210) is the primary test used internationally to estimate chronic fish toxicity in support of ecological risk assessments and chemical management programs.
Journal of Immunotoxicology, 2013
Krejsa CM, Neradilek MB, Polissar NL, Cox N, Clark D, Cowan L, ...
- HESI - Health and Environmental Sciences Institute
Non-human primates may be the only relevant species for pharmacology or toxicology studies of certain biologics, due to lack of activity in other species.
Environmental Toxicology and Chemistry, 2013
Nichols JW, Huggett DB, Arnot JA, Fitzsimmons PN, ...
- HESI - Health and Environmental Sciences Institute
Models were developed to predict the bioconcentration of well-metabolized chemicals by rainbow trout.
Environmental and Molecular Mutagenesis, 2013
Pfuhler S, Elespuru R, Aardema MJ, Doak SH, Maria Donner E, ...
- HESI - Health and Environmental Sciences Institute
A workshop addressing strategies for the genotoxicity assessment of nanomaterials (NMs) was held on October 23, 2010 in Fort Worth Texas, USA.
Toxicologic Pathology, 2013
Schultze AE, Walker DB, Turk JR, Tarrant JM, Brooks MB, Pettit SD
- HESI - Health and Environmental Sciences Institute
The Health and Environmental Sciences Institute Cardiac Biomarkers Working Group surveyed the pharmaceutical development community to investigate practices in assessing hemostasis, including detection of hypocoagulable and hyper coagulable states.
Toxicologic Pathology, 2013
Reagan WJ, York M, Berridge B, Schultze E, Walker D, Pettit S
- HESI - Health and Environmental Sciences Institute
Cardiac troponin (cTn) has been utilized to assess acute myocardial injury, but the cTn response in active/ongoing chronic injury is not well documented.
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