Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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Inter‐Laboratory Control Data for Reproductive Endpoints Required in the OPPTS 870.3800/OECD 416 Reproduction and Fertility Test

Birth Defects Research Part B: Developmental and Reproductive Toxicology, 2009

Marty MS, Allen B, Chapin RE, Cooper R, Daston GP, Flaws JA, ...
  • HESI - Health and Environmental Sciences Institute

The U.S. EPA revised the Reproduction and Fertility Effects Test Guideline (OPPTS 870.3800/OECD 416) in 1998, adding numerous endpoints in an effort to incorporate new methodologies, improve the sensitivity for detecting reproductive toxicants, and more efficiently utilize study animals.

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TCDD-Mediated Suppression of the In Vitro Anti-Sheep Erythrocyte IgM Antibody Forming Cell Response Is Reversed by Interferon-Gamma

Toxicological Sciences, 2009

North CM, Kim BS, Snyder N, Crawford RB, Holsapple MP, ...
  • HESI - Health and Environmental Sciences Institute

Suppression of humoral immune responses by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) has been well established to require the aryl hydrocarbon receptor; however, the downstream mechanisms for this immunotoxic response remain poorly understood.

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Current Challenges in the Evaluation of Cardiac Safety During Drug Development: Translational Medicine Meets the Critical Path Initiative

American Heart Journal, 2009

Piccini JP, Whellan DJ, Berridge BR, Finkle JK, Pettit SD, ...
  • HESI - Health and Environmental Sciences Institute

In October 2008, in a public forum organized by the Cardiac Safety Research Consortium and the Health and Environmental Sciences Institute, leaders from government, the pharmaceutical industry, and academia convened in Bethesda, MD, to discuss current challenges in evaluation of short- and long-term cardiovascular safety ...

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Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
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