Toxicological Sciences, 2005
Holsapple MP, Farland WH, Landry TD, Monteiro-Riviere NA, ...
- HESI - Health and Environmental Sciences Institute
This article summarizes a roundtable discussion held at the 2005 Society of Toxicology Annual Meeting in New Orleans, LA.
Journal of Immunotoxicology, 2020
Kamperschroer C, Shenton J, Lebrec H, Leighton JK, Moore PA, ...
Currently, there is a multitude of CD3 bispecifics with different molecular designs and binding properties in preclinical and clinical development for the treatment of liquid or solid tumors. The key safety concerns with CD3 bispecifics are excessive release of cytokines, which may translate to potentially life-threating ...
Journal of Immunotoxicology, 2012
Kawabata T, Weaver J, Thomas D, Rowe M, Wang F, Kamperschroer C, ...
- HESI - Health and Environmental Sciences Institute
Epstein-Barr virus (EBV)-associated lymphomas are a known risk for immunosuppressed individuals.
Journal of Immunotoxicology, 2012
Lebrec H, O’Lone R, Freebern W, Komocsar W, Moore P
- HESI - Health and Environmental Sciences Institute
While immunotoxicology evaluations are often conducted in either rodents or non-human primates, findings in standard toxicology studies may trigger additional investigations in dogs.
Toxicology and Applied Pharmacology, 2004
Holsapple MP, Paustenbach DJ, Charnley G, West LJ, Luster MI, ...
- HESI - Health and Environmental Sciences Institute
In recent years, there has been increasing regulatory pressure to protect the health of children, with the basic tenet being that children differ significantly from adults in their biological or physiological responses to chemical exposures.
Journal of Immunotoxicology, 2007
Bugelski PJ, Kim C
- HESI - Health and Environmental Sciences Institute
The primary T-cell-dependent antibody response (TDAR) to antigens is widely used as a functional test in immunotoxicology.
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