Transforming the Evaluation of Agrochemicals (TEA) Committee

Mission Statement

The mission of the committee is to establish a map supporting the development of fit-for-purpose safety evaluation for agrochemicals that is applicable to changing global, as well as local, needs for evaluation and regulatory decisions that can incorporate relevant evolving science inputs. See the full project map landscape here.

Working Groups

  • Review of the Regulatory Guideline

    Regulatory agencies from Australia, Canada, Europe, and the US assessed the use of various test guidelines in the context of agrochemical safety assessment to inform the frequency of use of various guidelines. The goal was to better understand why some tests are used more than others, what valuable information is obtained from these tests, and whether some of the most routinely used data could be obtained using new methods.

  • Conceptual Model Development

    Based on problem formulation and problem exploration exercises conducted in 2021, a conceptual model was developed. The model is being used as a guide to the project to help prioritize the work.

  • TEA Manuscript #1

    A sub-team worked on a manuscript describing the needs for a project like TEA, as well as expected outcomes. The manuscript was published in August 2022.

  • TEA Manuscript #2

    A new manuscript featuring the project’s conceptual model was initiated. The goal of this paper is to highlight similarities among regulatory jurisdictions, in the way they assess the safety of agrochemicals.

  • NAM Survey

    A survey was developed and deployed among industry members to inform what NAMs are typically used for R&D as well as product registration, and with what frequency.

  • Evaluation of the 90d Dog Study for Agrochemicals

    This initiative is a joint collaborative project between the HESI PBPK and TEA Committees that is aimed at evaluating the utility of the 90d dog study (OECD TG 409, OPPTS 870.3150) for agrochemical safety evaluation. The project builds on recent international work in this space and strives to identify under what conditions this study is needed to inform human health risk assessment of agrochemicals, with the ultimate goal of identifying conditions where the test can be safely waived within a weight of evidence approach.

HESI Staff

Leadership Team

  • Gina Hilton, PhD

    PETA International Science Consortium

  • John Doe, PhD

    Liverpool John Moores University

  • Marco Corvaro, PhD

    Corteva Agriscience

  • Rhian Cope, PhD, DABT, DABVT, FACTRA

    Australian Pesticides and Veterinary Medicines Authority

  • Richard Currie, PhD

    Syngenta

Committee Events

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TEA MATE Workshop

June 9, 2023

London, UK

The TEA Committee hosted their TEA MATE workshop on June 9th in London, UK. The purpose of the workshop was to identify and integrate relevant new science to enhance and advance the TEA project in the context of broader community engagement.

Read more

Society of Toxicology Meeting 2023

March 19, 2023 – March 23, 2023

Nashville, TN, USA

A number of HESI committees will have presentations and posters at the Society of Toxicology Meeting in Nashville, TN.

Read more

EFSA One2022

June 21, 2022 – June 24, 2022

Brussels, Belgium

A number of HESI committees presented posters at the EFSA One 2022 conference.

Read more

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Committee Publications

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Transforming the Evaluation of Agrochemicals

Pest Management Science, 2022

Wolf DC, Bhuller Y, Cope R, Corvaro M, Currie R, Doe J, Doi A, ...

This article summarizes the challenges associated with the modernization of agrochemical safety evaluation, proposes a potential roadmap, and seeks input and engagement from the broader community to advance this effort.

Read more

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