An insightful review by Kamperschoer et al. that provides an overview of the various methods for assessment of Cytotoxic T Lymphocytes (CTL) function in Non-Human Primates in the context of non-clinical safety assessment of immune-modulating therapeutic agents. You can find this publication in the Journal of Immunotoxicology. The link to the full article is included below.
Current approaches to evaluate the function of cytotoxic T-cells in non-human primates. Kamperschroer et al., (2023), Journal of Immunotoxicology, 20:1, DOI: 10.1080/1547691X.2023.2176952
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