Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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An Evaluation Framework for New Approach Methodologies (NAMs) for Human Health Safety Assessment

Regulatory Toxicology and Pharmacology, 2020

Stanley T. Parish, Michael Aschner, Warren Casey, Marco Corvaro, ...
  • HESI - Health and Environmental Sciences Institute

The need to develop new tools and increase capacity to test pharmaceuticals and other chemicals for potential adverse impacts on human health and the environment is an active area of development. The response to these challenges for a “paradigm shift” toward using new approach methodologies (NAMS) for safety assessment has ...

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Alternative Models for Carcinogenicity Testing

Toxicological Sciences, 2001

Cohen SM, Robinson D, MacDonald J
  • HESI - Health and Environmental Sciences Institute

The International Conference on Harmonisation Expert Working Group on Safety suggested that under certain circumstances, data from alternative assays could be used in safety evaluation in place of a second bioassay.

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Allergic Sensitization: Screening Methods

Clinical and Translational Allergy, 2014

Ladics GS, Fry J, Goodman R, Herouet-Guicheney C, ...
  • HESI - Health and Environmental Sciences Institute

Experimental in silico, in vitro, and rodent models for screening and predicting protein sensitizing potential are discussed, including whether there is evidence of new sensitizations and allergies since the introduction of genetically modified crops in 1996, the importance of linear versus conformational epitopes, and ...

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Allergic Sensitization: Host-Immune Factors

Clinical and Translational Allergy, 2014

van Ree R, Hummelshoj L, Plantinga M, Poulsen L, Swindle E
  • HESI - Health and Environmental Sciences Institute

Allergic sensitization is the outcome of a complex interplay between the allergen and the host in a given environmental context.

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Health and Environmental Sciences Institute (HESI)

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