Peer-Reviewed
Publications

Open access, peer-reviewed publications ensure that knowledge is a public good. HESI believes that accessible research is critical for equitable engagement, diverse collaboration, and increased interdisciplinary conversation. We strive to achieve open access on all publications, and more than 200 publications from HESI programs have been published in the last decade.

Impact of HESI Publications
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HESI workshop summary: Interpretation of developmental and reproductive toxicity endpoints and the impact on data interpretation of adverse events

Birth Defects Research, 2024

Green et al.

Output from the HESI DART workshop entitled, “Interpretation of Developmental and Reproductive Toxicology in Regulatory Contexts and Frameworks” has been published. The purpose of the workshop was to capture key consensus approaches used to assess DART risks associated with chemical and pharmaceutical product exposure ...

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Advancing botanical safety: A strategy for selecting, sourcing, and characterizing botanicals for developing toxicological tools

Food and Chemical Toxicology, 2024

Waidyanatha et al.

Increases in botanical use, encompassing herbal medicines and dietary supplements, have underlined a critical need for an advancement in safety assessment methodologies. This manuscript highlights: 1) Botanical Safety Consortium's strategy for botanical selection, sourcing, and preparation of extracts to be used in in ...

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Within-laboratory reproducibility of Ames test results: Are repeat tests necessary?

Environmental and Molecular Mutagenesis, 2024

Errol Zeiger, Constance A. Mitchell, Stefan Pfuhler, Yang Liao, ...

A cross-sector group of experts from the Health and Environmental Sciences Institutes (HESI)'s Botanical Safety Consortium (BSC) and Genetic Toxicology Technical Committee (GTTC) analyzed data from the National Toxicology Program (NTP) Ames test database to evaluate the need for repeat testing when assessing the ...

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