PBPK Models Committee

Mission Statement

The committee aims to address key needs related to physiologically based pharmacokinetic (PBPK) modeling practices and applications that could facilitate use of PBPK models more consistently within the risk assessment context.

HESI Staff

Leadership Team

  • Anna Lowit, PhD

    US Environmental Protection Agency

Committee Publications

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PBPK Model Reporting Template for Chemical Risk Assessment Applications

Physiologically-based pharmacokinetic (PBPK) modeling analysis does not stand on its own for regulatory purposes but is a robust tool to support drug/chemical safety assessment. While the development of PBPK models have grown steadily since their emergence, only a handful of models have been accepted to support regulatory ...

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