This study addresses a critical public health and regulatory issue: how to effectively detect and assess the mutagenic and carcinogenic risks posed by nitrosamine impurities in medications.
HESI GTTC Ring Trial: Concordance between Ames and Rodent Carcinogenicity Outcomes for N-Nitrosamines (NAs) with Rat and Hamster Metabolic Conditions
Regulatory Toxicology and Pharmacology, 2025