HESI In Vitro Genetic Toxicity (IVGT) Testing Workshop

The HESI Emerging Issues Subcommittee on the Relevance and Follow-up of Positive Results in in Vitro Genetic Toxicity Testing (IVGT) held an international workshop June 5-6, 2007, in Washington, DC.  The workshop was a follow-up to the subcommittee’s June, 2006 workshop, which examined ways to advance the basis for the interpretation of positive findings in in vitro assays, facilitate the development of follow-up testing strategies, and define criteria to determine the relevance to human health.   The 2007 workshop participants discussed and expanded upon four potential sub-group topic areas, set goals and timelines, and worked to propose a path forward for the committee.  The IVGT steering team is in the process of finalizing a workplan for the subcommittee and establishing membership for two main workgroups.