This workshop is a pre-GTTC Annual Meeting workshop to provide extra time to discuss 2020-21 Quantitative Analysis Working Group activities, as well as emerging challenges and upcoming milestones. The presentations will collectively cover a variety of topics and issues pertaining to the refinement of quantitative methods for interpretation of genetic toxicity dose-response data in a risk assessment context.
The virtual workshop is open to GTTC Committee participants only. Click here to learn more about the HESI GTTC Committee.
Welcome & Opening Remarks
Paul White, Health Canada, and E'Lissa Flores, HESI
Topic 1: Determination of Human Exposure Limits for Mutagenic Alkylnitrosamines
George Johnson, Swansea University, Swansea, UK
Topic 2: CES (Critical Effect Size) Values for In Vivo Mutagenicity Endpoints
Guangcho Chen, RIVM, Bilthoven, The Netherlands
Topic 3: Inter-Individual Variability in Human Sensitivity to Environmental Mutagens
Paul White, Health Canada (Intro)
Part 1: Results from Comparative Analyses of In Vitro Dose Response Data
Lauren Gallant, University of Ottawa, Ottawa, Canada
Part 2: Results from Comparative Analyses of Human DNA Repair Capacity (DRC)
Madison Bell, University of Ottawa, Ottawa, Canada
Topic 4: GToxPi - A Multi-Endpoint Data Synthesis and Visualization Tool
Steve Detringer, Litron Laboratories, Rochester, New York, USA
Andreas Zeller, Hoffman-La Roche
740 15th Street NW, Suite 600
Washington, DC 20005
Sign up for our monthly e-newsletter.