Emerging Systems Toxicology for the Assessment of Risk (eSTAR) Committee Videos

HESI Emerging Systems Toxicology for Assessment of Risk (eSTAR) Committee 2023 Annual Meeting

eSTAR Overview and Recent Achievements

OASIS (Omics for Assessing Signatures for Integrated Safety)

Molecular Point of Departure

Error Corrected Sequencing

Use of Single-cell sequencing at the US EPA




Reflection on Projects Presented and Future Directions

Emerging Systems Toxicology for Assessment of Risk Annual Meeting 2022

Dr. Brian Chorley & Dr. Deidre Dalmas Wilk

HESI eSTAR Annual Meeting Objectives

Dr. Mark Viant

HESI eSTAR: Progress in (metabol)omics-based chemical grouping

Dr. Peter Yuen & Dr. Tatiana Sharipova

HESI eSTAR: microRNA Biomarker

Dr. Henghong Li

HESI eSTAR: TgX DDI Biomarker Qualification

Dr. Kamin Johnson & Dr. Scott Auerbach

HESI eSTAR: Transcriptomic POD

Dr. Chris Corton & Dr. Keith Tanis

HESI eSTAR: Carcinogenomics Project

Dr. Ali Ebrahimi

Understanding Cell Biology and Toxicology with Spatial Transcriptomics: use Cases and Bioinformatic Platforms

Other eSTAR Videos

Dr. Leah Wehmas

Genomics from Formalin-Fixed Paraffin Embedded Tissue Samples: Methods and Lessons Learned for Risk Assessment

Dr. Jurek Kozyra from Nanovery

Nucleic Acid Nanorobotics: A Novel Approach to MicroRNA Quantification

Dr. Subham Dasgupta

Dasgupra miRNA/mRNA Profiling

Dr. Weida Tong, FDA NCTR

Tox-GAN: An AI Approach Alternative to Animal Studies – a Case Study with Toxicogenomics

Feb 17, 2022

Dr. David Rouquie, Bayer

Interplay between chemical and biological spaces: opportunities for toxicity prediction and compound de novo design

June 7, 2021

Dr. Ruchir Shah, Sciome

Transcriptomics read across for mechanism of action characterization

April 19, 2021

Dr. Jessica Ewald, McGill University

FASTBMD: an Online Tool for Rapid Benchmark Dose-Response Analysis of Transcriptomics Data

March 9, 2021

Dr. Jason O’Brien, Environment and Climate Change Canada

Transcriptomic Point of Departure (tPOD):​ Review of Chemical Domains, Experimental Design and Comparison to Long-term Apical Effect Concentrations

December 10, 2020

Dr. Richard Currie, Syngenta

Elaborating & Quantifying the DARTable genome for prediction of Teratogenic Doses.

August 4, 2020

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