This study addresses variability challenges in the Amphibian Metamorphosis Assay (AMA), a widely used assay to detect the endocrine-disrupting effects of chemicals on the thyroid system. By analyzing data from 52 studies across seven laboratories, the paper highlights how variability in controls affects the assay's ...
Control Performance of Amphibian Metamorphosis Assays with Xenopus laevis
Regulatory Toxicology and Pharmacology, 2025