Download the COMPARE Allergen Database

The COMprehensive Protein Allergen REsource (COMPARE) database is a rigorously curated, open-access resource developed to support the global safety evaluation of novel proteins. It is especially relevant for assessing potential allergenicity in genetically modified organisms (GMOs), novel foods, and biopharmaceutical products. The database is updated annually by an international scientific steering team, following a transparent and peer-reviewed process.

COMPARE is hosted and maintained by the Health and Environmental Sciences Institute (HESI) with contributions from leading experts in allergy research, bioinformatics, and regulatory science.

🔗 Access the public interface here: https://comparedatabase.org/

Request the COMPARE 2026 Database

To download the COMPARE 2026 data package, which includes:

  • A FASTA file of allergen protein sequences
  • An Excel (.xls) file containing associated metadata (e.g., accession numbers, species, supporting literature references)

please complete the form below.

✅ Academic and Government Users: Free access
💼 Industry, NGOs, and Consultants: A $1,000 USD fee helps supports maintenance and sustainability of the database.

Files will be delivered via email to the address provided.

For questions or assistance, please contact:
📧 compare@hesiglobal.org

If you are an employee at BASF, Bayer, Corteva or Syngenta, select "COMPARE Steering Team Member".

Become a COMPARE Steering Team Member!

There is value in being a COMPARE Stakeholder:

  • Network with allergen experts monthly
  • Have a seat at the table – contribute your input
  • Ensures the ongoing sustainability of this resource
  • Membership fees are based on companies worldwide sales
  • To become a member of the COMPARE Steering Team email compare@hesiglobal.org

COMPARE 2026 Steering Team Members:

  • Academic Medical Center, University of Amsterdam
  • BASF
  • Bayer
  • Corteva Agriscience™
  • Syngenta
  • US Environmental Protection Agency
  • US Food and Drug Administration
  • Zhejiang University, China

Contact Us

Health and Environmental Sciences Institute (HESI)

hesi@hesiglobal.org
Phone: +1-202-659-8404
Fax: +1-202-659-8403

740 15th Street NW, Suite 600
Washington, DC 20005

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