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Upcoming Events

FDA/CDER-HESI Workshop on Preclinical and Translational Safety Assessment of CD3 Bispecifics

Silver Spring, Maryland, USA

With the emergence of CD3 bispecifics as a novel weapon in the fight against cancer, there is a growing need to share information and learnings about these compounds that range from strategies for target expression profiling to nonclinical safety assessment to clinical experience. This workshop is designed to engage with a multi-stakeholder group of experts that will present and discuss their case examples with the objectives of learning from each other through robust engagement and discussion to enable the best outcomes for patients

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				FAAM Workshop Logo_revised large 4
			
						REGISTRATION HERE
					
			
						DRAFT MEETING AGENDA
					
	

Details
Location: Tivoli Hotel and Congress Center - Copenhagen, Denmark
Dates: October 17 - 18, 2018

Another food safety and allergy meeting, the EAACI 2018 FAAM meeting will be held October 18 - 20 in Copenhagen, please consider attending both events!

About
In the growing field of allergy research, scientists can approach protein characterization and allergy hazard assessment in diverse ways. The Health and Environmental Sciences Institute (HESI) Protein Allergens, Toxins, and Bioinformatics (PATB) committee supports original basic research that seeks to uncover the interplay between protein allergenicity and the physicochemical properties of allergenic proteins. The PATB also oversees the creation, maintenance and distribution of the Comprehensive Protein Allergen Resource (COMPARE) Database whose use in conjunction bioinformatic tools, offers an effective means for assessing allergenic potential of novel food proteins.  PATB’s focus on basic allergy research, coupled with bioinformatic methods for allergenic hazard assessment is unique within the scientific community as it supports an ever-increasing awareness of allergenicity among consumers and regulators. Topics to be covered in this workshop will include historic aspects of food allergy assessment, the evolution of bioinformatics as it relates to allergy assessment, and recent changes in regulations regarding novel food proteins.

This educational workshop will cover advances in protein allergy research and inform the use of novel approaches for the identification of potential food allergens. This event will be of interest to government regulators, those involved in food allergy and celiac disease research, and scientists involved in food safety and risk assessment.

dreamstime_xl_71979237

 

Objectives

Evaluate bioinformatics approaches to characterize the allergenicity potential of novel proteins and inform allergy safety assessment.

Discuss real-world examples of: 1) a product development case-study describing the utility of bioinformatics in protein characterization, and 2) a practical application of the EFSA 2017 Guidance.

Provide insights from new research, ranging from modifications of allergen epitopes at the single amino-acid level, to using protein structural modeling for allergenicity prediction, to the relation between enzymes and allergenic activity.

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Related Events

 

2018 Safety Pharmacology Society (SPS) Annual Meeting
Marriott Wardman Park
Washington, DC
September 30–October 3, 2018

For more information regarding the agenda and to register for the meeting, please visit the website.