Events

Upcoming Events

CT-TRACS & Cell and Gene Therapy Joint Workshop: “Safety assessment of cell therapy products: current advances and challenges”

London, UK

HESI’s Cell Therapy–TRAcking, Circulation, & Safety (CT-TRACS) Committee is honored to present the first workshop of the new Cell and Gene Therapy Catapult seminar series.

Topics and Learning Objectives:

1. Future needs in patient safety of cell-based therapies. Identify challenges and opportunities to enhance the accuracy and efficiency of safety assessment of cell therapy products. Perspectives from a broad range of stakeholders from design to implementation settings.

2. Evolving safety tools and applied safety techniques. Learn about in vivo cell tracking approaches and their role in supporting clinical translation, as well as methods for evaluating the potential tumorigenicity risk of cell-based therapeutic products.

3. Role of collaboration in cell therapy development and use. Explore international opportunities to bridge stakeholders and improve our ability to develop and implement effective standards.

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T-cell Biology and Application to Immunopharmacology and Immunotoxicology Course

Munich , Germany

The field of immunotoxicology is a dynamic one in which changing public health concerns, novel biomedical research advances, and innovative technological developments constantly change the landscape and the way in which work is carried out and utilized. As this field requires combined expertise in both immunology and toxicology, the need for continued training and interdisciplinary interactions are critical for those who work within this field. This is essential both for those with an immunology background who seek to apply this expertise to drug development and safety, as well as those who wish to enhance their current drug safety expertise with a deeper understanding of immunology.

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The Gut Microbiome Workshop

Alexandria, VA, United States

A 2-day workshop to address the state of the science and data gaps in gut microbiome research.

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				medium dreamstime image
	

 

The Gut Microbiome: Markers of Human Health,

Drug Efficacy and Xenobiotic Toxicity

The gut microbiome is believed to play an important role in human health in areas as diverse as brain function and the immune system.  Exploring host-microbiome interactions will provide a mechanistic understanding and enable new insights in human diseases (i.e., their diagnosis, prognosis and treatment) and new perceptions of xenobiotic efficacy and/or toxicity. This workshop will review the science and initiate discussions on multiple topics, including a) identification of biomarkers of toxicity for alterations in gut microbial function, b) if changes in the microbiome can affect efficacy of medicines and c) if exposure to xenobiotics can eventually result in a disease state through changes in the microbiome.  Conclusions from his workshop will help determine where the data gaps are so that researchers can start answering these questions.

WORKSHOP GOAL
To identify data gaps that can be addressed to help determine if alterations in the gut microbiome have an effect on human health.

guthealth

WORKSHOP AIMS
1.  To discuss and review the current science on the gut microbiome and identify areas of interest regarding its role in human health
2.  To discuss our understanding on how xenobiotic toxicity affects the microbiome
3.  To understand if there are biomarkers of disease or organ damage due to:
     -  Alterations of microbiome structure and function
     -  Endogenous microbial metabolites

CONFIRMED SPEAKERS 

Elena Biagi, University of Bologna                Kun Lu, University of North Carolina, Chapel Hill
Carrie Brodmerkel, Janssen                           Jeremy Nicholson, Imperial College London   
Mark Brown, Cleveland Clinic                        Andrew Patterson, Pennsylvania State University
Carl Cerniglia, US FDA, NCTR                        Gary Perdew, Pennsylvania State University
Eugene Chang, University of Chicago           Joseph Petrosino, Baylor College of Medicine
Julia Cui, University of Washington              Nathan Price, Institute for Systems Biology
Anna Mae Diehl, Duke University                  Mohan Raizada, University of Florida
Rodney Dietart, Cornell University                Barbara Reherhman, NIDDK
Aaron Erickson, University of Missouri
Marijke Faas, University of Groningen

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REGISTRATION WILL OPEN IN EARLY 2018.

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